Document Detail

Choosing an antihypertensive combination with a more efficient central blood pressure reduction.
MedLine Citation:
PMID:  21090926     Owner:  NLM     Status:  In-Process    
Not all blood pressure (BP)-lowering agents have the same effect on central BP, but we know that central BP, in itself, is a risk factor for cardiovascular diseases. Therefore, antihypertensive agents should ideally also have a central BP-lowering effect. In this paper the authors evaluate the effect of adding a calcium channel blocker to a β-blocker. The results show this combination does not reverse the lesser effect of β-blockers on central BP, and that the combination of valsartan plus amlodipine is more effective in lowering central BP than a combination of amlodipine plus atenolol.
Miguel Camafort-Babkowski
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Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Expert review of cardiovascular therapy     Volume:  8     ISSN:  1744-8344     ISO Abbreviation:  Expert Rev Cardiovasc Ther     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101182328     Medline TA:  Expert Rev Cardiovasc Ther     Country:  England    
Other Details:
Languages:  eng     Pagination:  1523-5     Citation Subset:  -    
Hospital de Móra d'Ebre, Internal Medicine Department, c/o Benet Messeguer, E-43740 Móra d'Ebre, Spain.
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MeSH Terms
Comment On:
Hypertension. 2010 Jun;55(6):1314-22   [PMID:  20404219 ]

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