Document Detail


Chondrosarcoma of the nasal septum: skull base imaging and clinicopathologic correlation.
MedLine Citation:
PMID:  8758626     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Chondrosarcoma arising in the head and neck and craniofacial region is an uncommon lesion. The nasal septum is a particularly rare site of origin, with approximately 30 cases previously reported in the English literature. We present six new cases of chondrosarcoma arising in the nasal septum. Each of these tumors required cranial base surgical approaches for removal. Current imaging techniques allow a very accurate diagnosis to be made before biopsy. The characteristic ring-forming calcifications seen on computed tomography scans can be correlated with the histologic pattern of calcification. Magnetic resonance imaging techniques allow precise definition of tumor extent, which is particularly important because the disease is best treated with primary surgery. Advances in imaging and surgical techniques allow a much more complete tumor removal. It is hoped that this will increase the likelihood of cure in these patients. Surgical management and indications for adjuvant therapy are discussed.
Authors:
C H Rassekh; D W Nuss; S B Kapadia; H D Curtin; J L Weissman; I P Janecka
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery     Volume:  115     ISSN:  0194-5998     ISO Abbreviation:  Otolaryngol Head Neck Surg     Publication Date:  1996 Jul 
Date Detail:
Created Date:  1996-09-16     Completed Date:  1996-09-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8508176     Medline TA:  Otolaryngol Head Neck Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  29-37     Citation Subset:  IM    
Affiliation:
Department of Otolaryngology, University of Texas Medical Branch, Galveston, TX 77555-0521, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Biopsy
Calcinosis / diagnosis,  pathology,  radiography
Chondrosarcoma / diagnosis,  pathology*,  radiography,  surgery
Craniotomy / methods
Female
Headache / diagnosis
Humans
Magnetic Resonance Imaging*
Male
Middle Aged
Nasal Obstruction / diagnosis
Nasal Septum / pathology*,  radiography,  surgery
Neoplasm Invasiveness
Nose Neoplasms / diagnosis,  pathology*,  radiography,  surgery
Radiotherapy, Adjuvant
Skull Neoplasms / diagnosis,  pathology,  radiography,  surgery
Tomography, X-Ray Computed*

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