| Chondrosarcoma of the nasal septum: skull base imaging and clinicopathologic correlation. | |
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MedLine Citation:
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PMID: 8758626 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Chondrosarcoma arising in the head and neck and craniofacial region is an uncommon lesion. The nasal septum is a particularly rare site of origin, with approximately 30 cases previously reported in the English literature. We present six new cases of chondrosarcoma arising in the nasal septum. Each of these tumors required cranial base surgical approaches for removal. Current imaging techniques allow a very accurate diagnosis to be made before biopsy. The characteristic ring-forming calcifications seen on computed tomography scans can be correlated with the histologic pattern of calcification. Magnetic resonance imaging techniques allow precise definition of tumor extent, which is particularly important because the disease is best treated with primary surgery. Advances in imaging and surgical techniques allow a much more complete tumor removal. It is hoped that this will increase the likelihood of cure in these patients. Surgical management and indications for adjuvant therapy are discussed. |
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Authors:
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C H Rassekh; D W Nuss; S B Kapadia; H D Curtin; J L Weissman; I P Janecka |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery Volume: 115 ISSN: 0194-5998 ISO Abbreviation: Otolaryngol Head Neck Surg Publication Date: 1996 Jul |
Date Detail:
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Created Date: 1996-09-16 Completed Date: 1996-09-16 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8508176 Medline TA: Otolaryngol Head Neck Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 29-37 Citation Subset: IM |
Affiliation:
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Department of Otolaryngology, University of Texas Medical Branch, Galveston, TX 77555-0521, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Biopsy Calcinosis / diagnosis, pathology, radiography Chondrosarcoma / diagnosis, pathology*, radiography, surgery Craniotomy / methods Female Headache / diagnosis Humans Magnetic Resonance Imaging* Male Middle Aged Nasal Obstruction / diagnosis Nasal Septum / pathology*, radiography, surgery Neoplasm Invasiveness Nose Neoplasms / diagnosis, pathology*, radiography, surgery Radiotherapy, Adjuvant Skull Neoplasms / diagnosis, pathology, radiography, surgery Tomography, X-Ray Computed* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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