| Chondrogenic differentiation of adult MSCs. | |
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MedLine Citation:
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PMID: 22563661 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Chondrogenesis is a vital part of adult life, as cartilage is important not only for articulation of joints but also maintenance functions of the body. Chondrogenesis is a five way process of intricate events controlled by specific genes and cell-cell interactions which has been documented over recent years. This review highlights the current literature regarding the process of endochondral ossification and covers the different level of control at agent level. Due to the proliferative nature of chondrogenesis and using chondrocytes for self renewal and repair, current research involves finding ways in which to improve and replicate expansion of chondrocytes. The review summarises ways in which ex vitro expansion can be manipulated using growth factors, external sources and scaffolds. |
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Authors:
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M Griffin; Hindocha Sandip; W S Khan |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-5-8 |
Journal Detail:
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Title: Current stem cell research & therapy Volume: - ISSN: 1574-888X ISO Abbreviation: - Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-5-8 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101272517 Medline TA: Curr Stem Cell Res Ther Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Plastic Surgery, Whiston Hospital, Warrington Road, L355DR, UK. Hindocha2001@yahoo.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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