| Cholinesterase inhibitory constituents from Ficus bengalensis. | |
| | |
MedLine Citation:
|
PMID: 23106601 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Bengalensinone (22β-hydroxylup-12,20-dien-3-one; 1), a new lupane triterpene, and benganoic acid (2), a new apocarotenoid, together with lupanyl acetate, 3-acetoxy-9(11),12-ursandiene, stigmasterol, alpinumisoflavone, 4-hydroxyacetophenone, 4-hydroxybenzoic acid, 4-hydroxymellein, and p-coumeric acid were isolated from the methanolic extract of the aerial roots of Ficus bengalensis. The structures of these compounds were established by the combination of 1D NMR ((1)H and (13)C NMR) and 2D NMR (HMQC, HMBC, and COSY) analyses, and mass spectrometry (EI-MS and HR-EI-MS), and in comparison with literature data of the related compounds. Compounds 1 and 2 displayed inhibitory potential against enzyme cholinesterase in a concentration-dependent manner with IC(50) values 194.5 and 154.5 μM for acetylcholinesterase and 224.9 and 120.0 μM for butyrycholinesterase, respectively. |
| | |
Authors:
|
Naheed Riaz; Muhammad Akram Naveed; Muhammad Saleem; Bushra Jabeen; Muhammad Ashraf; Syeda Abida Ejaz; Abdul Jabbar; Ishtiaq Ahmed |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-10-29 |
Journal Detail:
|
Title: Journal of Asian natural products research Volume: - ISSN: 1477-2213 ISO Abbreviation: J Asian Nat Prod Res Publication Date: 2012 Oct |
Date Detail:
|
Created Date: 2012-10-30 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100888334 Medline TA: J Asian Nat Prod Res Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
a Department of Chemistry , Baghdad-ul-Jadeed Campus, The Islamia University of Bahawalpur , Bahawalpur , 63100 , Pakistan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Comorbidities and survival in obstructive sleep apnoea beyond the age of 50.
Next Document: Electrostatic spray deposition of porous SnO2/graphene anode films and their enhanced lithium storag...