| Cholinergic crisis after rodenticide poisoning. | |
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MedLine Citation:
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PMID: 21293782 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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Rodenticides have historically been common agents in attempted suicides. As most rodenticides in the United States (U.S.) are superwarfarins, these ingestions are generally managed conservatively with close monitoring for coagulopathy, and if necessary, correction of any resulting coagulopathy. However, alternate forms of rodenticides are imported illegally into the U.S. and may be ingested either accidentally or in suicide attempts. We present an unusual case of poisoning by the illegally imported rodenticide, "Tres Pasitos." The main ingredient of this rat poison is aldicarb, a potent carbamate pesticide that causes fulminant cholinergic crisis. This case is relevant and timely because carbamates and organophosphates are still used as insecticides and emergency physicians (EP) working in rural areas may have to evaluate and manage patients with these poisonings. As international travel and immigration have increased, so has the possibility of encountering patients who have ingested toxic substances from other countries. In addition, there has been increased concern about the possibility of acts of terrorism using chemical substances that cause cholinergic toxidromes.1,2 EPs must be able to recognize and manage these poisonings. This report describes the mechanism of action, clinical manifestations, laboratory evaluation and management of this type of poisoning. The pertinent medical literature on poisoning with aldicarb and similar substances is reviewed. |
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Authors:
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Muhammad Waseem; Christopher Perry; Scott Bomann; Meena Pai; Joel Gernsheimer |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The western journal of emergency medicine Volume: 11 ISSN: 1936-9018 ISO Abbreviation: West J Emerg Med Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2011-02-04 Completed Date: 2011-07-14 Revised Date: 2011-07-25 |
Medline Journal Info:
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Nlm Unique ID: 101476450 Medline TA: West J Emerg Med Country: United States |
Other Details:
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Languages: eng Pagination: 524-7 Citation Subset: - |
Affiliation:
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Lincoln Medical & Mental Health Center, Bronx, New York. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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