| Cholesterol and vitamins: revisited study. | |
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MedLine Citation:
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PMID: 22217984 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The link between low density lipoprotein and coronary heart disease has been widely studied. Oxidized LDL damages the artery wall, and a diet rich in vitamins and low in saturated fat and cholesterol may reduce this risk. Not only hypercholesterolemia but also low levels of high density lipoprotein cholesterol are critical risk factors for atherosclerosis and related diseases. It has been reported that high doses of B complex vitamin may be useful in lowering blood cholesterol and triglyceride levels in the body, however the use of this compound has been limited by an annoying flush and concern for toxicity. Niacin is a B-complex vitamin with anti-atherosclerotic properties and is an effective medication for raising high density lipoprotein. The combination of niacin with other lipid-lowering drugs, such as statins, reduces the dynamic of atherosclerosis disease. In addition, vitamin E is one of the most important lipid soluble anti-oxidants in humans, and reduces atherosclerosis plaque, coronary artery diseases and myocardial infarction. Vitamin E protects the integrity of membranes by inhibiting lipid peroxidation. In this study we revisited the interrelationship between cholesterol, low density lipoproteins and vitamins. |
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Authors:
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A Saggini; A Anogeianaki; D Angelucci; E Cianchetti; M D'Alessandro; G Maccauro; V Salini; A Caraffa; S Teté; F Conti; D Tripodi; M Fulcheri; S Frydas; Y B Shaik-Dasthagirisaheb |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of biological regulators and homeostatic agents Volume: 25 ISSN: 0393-974X ISO Abbreviation: J. Biol. Regul. Homeost. Agents Publication Date: 2011 Oct-Dec |
Date Detail:
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Created Date: 2012-01-05 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8809253 Medline TA: J Biol Regul Homeost Agents Country: Italy |
Other Details:
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Languages: eng Pagination: 505-15 Citation Subset: IM |
Affiliation:
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Department of Dermatology, University of Rome Tor Vergata, Rome, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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