| Cholesterol and triglyceride management: "if I take my medication, can I eat what I want?". | |
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MedLine Citation:
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PMID: 20386249 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The medications we use for cholesterol and triglyceride lowering are powerful and have substantial outcome data. However, even with aggressive statin therapy, there is residual risk for recurrent cardiovascular events. Strict dietary modification has been shown to reduce low-density lipoprotein (LDL) cholesterol by 20% to 30%. Low-fat and Mediterranean-type diets have also been associated with atherosclerosis regression and fewer coronary heart disease events. On the other hand, a high-fat diet can produce postprandial lipemia and an increase in cardiovascular disease risk. Patients with atherogenic dyslipidemia (low high-density lipoprotein cholesterol, increased triglycerides and non-high-density lipoprotein cholesterol, small dense low-density lipoprotein particles) and visceral adiposity are particularly prone to postprandial lipemia. These individuals typically have insulin resistance, which is associated with endothelial dysfunction and an increased risk for thrombosis. Lifestyle intervention is the key to reducing postprandial lipemia, specifically weight reduction and increased physical activity. Although medications can improve postprandial lipemia, poor dietary choices can overwhelm the effects of medication and negatively impact the health of arteries, thus promoting atherosclerosis. Therefore, patients who are treated with medications for dyslipidemia must be counseled on consuming a heart-healthy diet. |
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Authors:
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Lynne T Braun |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of cardiovascular nursing Volume: 25 ISSN: 1550-5049 ISO Abbreviation: J Cardiovasc Nurs Publication Date: 2010 May-Jun |
Date Detail:
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Created Date: 2010-04-13 Completed Date: 2010-07-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8703516 Medline TA: J Cardiovasc Nurs Country: United States |
Other Details:
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Languages: eng Pagination: 241-6 Citation Subset: IM; N |
Affiliation:
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Rush University Medical Center, Chicago, Illinois 60612, USA. lynne_t_braun@rush.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cardiovascular Diseases
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etiology,
prevention & control* Counseling Diet, Fat-Restricted* Diet, Mediterranean* Exercise Food Habits Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use Hypercholesterolemia / complications, drug therapy*, prevention & control Hypertriglyceridemia / complications, drug therapy*, prevention & control Life Style Patient Compliance* Patient Education as Topic Practice Guidelines as Topic Risk Factors Risk Reduction Behavior Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Hydroxymethylglutaryl-CoA Reductase Inhibitors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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