Document Detail


Cholesterol oxidation in meat-based baby foods.
MedLine Citation:
PMID:  15164848     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cholesterol oxidation in commercial meat-based homogenized and freeze-dried baby foods was examined. The 7 major products of this reaction were determined by gas chromatography coupled with mass spectrometry (GC-MS). As far as single cholesterol oxidation products (COP) are concerned, 7-ketocholesterol was the major product of direct cholesterol oxidation in the 2 groups of analyzed samples, and this study confirmed that it is a useful marker of the whole cholesterol oxidation process. Nevertheless, the amounts of cholesterol-5beta,6beta-epoxide were often similar to and sometimes higher than the amounts of 7-ketocholesterol, thus showing a strong development of both direct and indirect cholesterol oxidation pathways. Total COP content was significantly higher in freeze-dried than in homogenized products. Moreover, in freeze-dried samples, the COP content per serving was quite variable and, in 2 samples, it was close to or even higher than 500 microg. The greater development of cholesterol oxidation in the freeze-dried samples was confirmed by their highest total COP/cholesterol percent ratios. A constant correlation between the fatty acid composition and the development of cholesterol oxidation was not found, although a positive correlation between unsaturated fatty acid content and total COP content occasionally exists in samples of the same brand.
Authors:
Filippo Evangelisti; Paola Zunin; Raffaella Boggia; Claudio Calcagno
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of AOAC International     Volume:  87     ISSN:  1060-3271     ISO Abbreviation:  J AOAC Int     Publication Date:    2004 Mar-Apr
Date Detail:
Created Date:  2004-05-28     Completed Date:  2004-08-24     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  9215446     Medline TA:  J AOAC Int     Country:  United States    
Other Details:
Languages:  eng     Pagination:  505-10     Citation Subset:  IM    
Affiliation:
University of Genova, Dipartimento di Chimica e Tecnologie Farmaceutiche e Alimentari, Via Brigata Salerno (ponte), 16147 Genova, Italy. evangelisti@dictfa.unige.it
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MeSH Terms
Descriptor/Qualifier:
Animals
Cholesterol / metabolism*
Humans
Infant
Infant Food / analysis*
Infant, Newborn
Meat Products / analysis*
Oxidation-Reduction
Chemical
Reg. No./Substance:
57-88-5/Cholesterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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