| Cholesterol-lowering benefits of oat-containing cereal in Hispanic americans. | |
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MedLine Citation:
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PMID: 15942550 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This randomized, controlled trial of cholesterol lowering by an oat bran cereal containing beta glucan vs a corn cereal without soluble fiber in Hispanic Americans was conducted for 11 weeks. One-hundred fifty-two men and women, ages 30 to 70 years, with baseline low-density lipoprotein cholesterol (LDL-C) levels between 120 and 190 mg/dL and triglycerides <400 mg/dL were included. After eating a National Cholesterol Education Program Step 1 diet for 5 weeks, subjects were randomly assigned to the corn or the oat cereal for the next 6 weeks. The daily dose of beta glucan was 3 g. Consumption of oat cereal was associated with a reduction in plasma levels of both total cholesterol (-10.9+/-21.6 mg/dL; -4.5%) and LDL-C (-9.4+/-20.3 mg/dL; -5.3%). Consumption of corn cereal did not affect either total cholesterol (+1.2+/-18.3 mg/dL; 1.1%) or LDL-C (+1.2+/-17.5 mg/dL; 2.2%). Differences between the effects of the two cereals on total cholesterol and LDL-C were significant, P =.0003 and P =.0007, respectively. |
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Authors:
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Wahida Karmally; Maria G Montez; Walter Palmas; Wendy Martinez; Anita Branstetter; Rajasekhar Ramakrishnan; Steve F Holleran; Steven M Haffner; Henry N Ginsberg |
Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of the American Dietetic Association Volume: 105 ISSN: 0002-8223 ISO Abbreviation: J Am Diet Assoc Publication Date: 2005 Jun |
Date Detail:
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Created Date: 2005-06-08 Completed Date: 2005-08-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7503061 Medline TA: J Am Diet Assoc Country: United States |
Other Details:
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Languages: eng Pagination: 967-70 Citation Subset: AIM; IM |
Affiliation:
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The Irving Center for Clinical Research, Columbia University Medical Center, New York, NY 10032, USA. wk2@columbia.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Anticholesteremic Agents / administration & dosage*, therapeutic use Avena sativa* / chemistry Cereals Cholesterol / blood Cholesterol, HDL / blood Cholesterol, LDL / blood Female Hispanic Americans* Humans Hypercholesterolemia / blood, diet therapy* Male Middle Aged Treatment Outcome Triglycerides / blood beta-Glucans / administration & dosage*, therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Anticholesteremic Agents; 0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Triglycerides; 0/beta-Glucans; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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