| Cholesterol, lipoproteins, and cognitive impairment. | |
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MedLine Citation:
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PMID: 21291838 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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This article discussed the central role of the deposition of amyloid beta in the pathogenesis of Alzheimer disease. (AD), and the animal data which supports the role of cholesterol on its deposition. The effect of mid-life cholesterol is discussed, and the presence of cardiovascular disease risk factors in the patients with evidence for AD and vascular disease. The role of statin therapy is mentioned, although concrete evidence in controlled prospective trials has not been published in a large trial. The value of hygienic approaches including exercise, diet and behavioral changes is mentioned. Currently there are no safe and effective drugs which have been proven to reduce the incidence or the progression of AD, although research in this important area is ongoing. |
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Authors:
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David T Nash |
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Publication Detail:
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Type: Journal Article Date: 2009-10-23 |
Journal Detail:
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Title: Journal of clinical lipidology Volume: 3 ISSN: 1933-2874 ISO Abbreviation: J Clin Lipidol Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2011-02-04 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101300157 Medline TA: J Clin Lipidol Country: United States |
Other Details:
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Languages: eng Pagination: 368-71 Citation Subset: - |
Affiliation:
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Syracuse Preventive Cardiology, 600 East Genesee Street, Syracuse, NY 13202, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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