Document Detail


Cholesterol biosynthesis and progesterone production by chorionic cells of the early sheep conceptus in vitro.
MedLine Citation:
PMID:  494367     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Dissociated trophoblast cells from the chorion of the 21-day sheep conceptus were shown to produce progesterone in vitro. Evidence that this represented synthesis de novo was provided by the prolonged production of progesterone in the absence of added precursor steroids. Radioactive cholesterol was isolated after incubation of dispersed chorionic cells with acetate-1-14C.
Authors:
G J Marcus; L Ainsworth; R Lucis
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Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  Steroids     Volume:  34     ISSN:  0039-128X     ISO Abbreviation:  Steroids     Publication Date:  1979 Sep 
Date Detail:
Created Date:  1979-12-27     Completed Date:  1979-12-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0404536     Medline TA:  Steroids     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  295-303     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Acetates / metabolism
Animals
Cholesterol / biosynthesis*
Chorion / metabolism*
Female
Pregnancy
Progesterone / biosynthesis*
Sheep / metabolism
Chemical
Reg. No./Substance:
0/Acetates; 57-83-0/Progesterone; 57-88-5/Cholesterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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