| Cholesterol absorption: influence of body weight and the role of plant sterols. | |
| | |
MedLine Citation:
|
PMID: 16256005 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Cholesterol absorption and synthesis are inter-regulated, so if one changes then the other changes in the opposite direction. The regulation and detailed mechanism of cholesterol absorption have been intensely investigated. Inhibition of cholesterol absorption has become an additional factor for cholesterol lowering. Agents inhibiting cholesterol absorption, mainly plant stanols and sterols or ezetimibe, usually lower low-density lipoprotein cholesterol in monotherapy by less than 20%, indicating that these inhibitors can normalize cholesterol levels only in patients with a modest baseline hypercholesterolemia. Body weight, especially obesity with and without diabetes, and dietary plant sterols alter cholesterol absorption differently. This article briefly reviews some special questions of cholesterol absorption under these conditions. |
| | |
Authors:
|
Helena Gylling; Tatu A Miettinen |
Related Documents
:
|
7104375 - Effect of sterol structure on the transfer of sterols and phospholipids from liposomes ... 6529445 - Effects of feeding cholesterol and mixed plant sterols on the fecal excretion of acidic... 15989725 - The effect of plant stanol- and sterol-enriched foods on lipid metabolism, serum lipids... 16392705 - Dietary lectin lowers serum cholesterol and raises fecal neutral sterols in cholesterol... 22061985 - Effects of vitamin e supplementation on performance and meat quality traits of morkaram... 11719955 - Feeding aggregation of the tick rhipicephalus appendiculatus (ixodidae): benefits and c... |
Publication Detail:
|
Type: Comparative Study; Journal Article; Review |
Journal Detail:
|
Title: Current atherosclerosis reports Volume: 7 ISSN: 1523-3804 ISO Abbreviation: Curr Atheroscler Rep Publication Date: 2005 Nov |
Date Detail:
|
Created Date: 2005-10-31 Completed Date: 2006-04-26 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 100897685 Medline TA: Curr Atheroscler Rep Country: United States |
Other Details:
|
Languages: eng Pagination: 466-71 Citation Subset: IM |
Affiliation:
|
Division of Internal Medicine, Department of Medicine, University of Helsinki, Biomedicum Helsinki, PO Box 700, FIN-00029, Helsinki, Finland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Absorption
/
drug effects Body Mass Index Body Weight* Cholesterol / blood, metabolism* Cholesterol, HDL / drug effects, metabolism Cholesterol, LDL / drug effects, metabolism Female Humans Male Phytosterols / metabolism, therapeutic use* Prognosis Sensitivity and Specificity Treatment Outcome |
| Chemical | |
Reg. No./Substance:
|
0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Phytosterols; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Influence of dietary carbohydrate and fat on LDL and HDL particle distributions.
Next Document: Gender differences in lipoprotein metabolism and dietary response: basis in hormonal differences and...