| Choledocholithiasis: diagnosis with oral-contrast-enhanced CT cholangiography. | |
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MedLine Citation:
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PMID: 10587126 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The objective of this investigation was to assess the performance of helical CT cholangiography after administration of an oral biliary contrast agent for the diagnosis of choledocholithiasis. SUBJECTS AND METHODS: Helical CT cholangiography was performed on 31 patients referred for endoscopic retrograde cholangiography of suspected choledocholithiasis. Iopanoic acid (6 g) was administered orally 8-12 hr before acquisition of helical CT cholangiograms. Three-dimensional and two-dimensional reformations were generated from a set of axial source images. Two radiologists independently interpreted the helical CT cholangiograms. Sensitivity and specificity were calculated using findings on retrograde cholangiography as the standard of reference. In addition, interobserver agreement was determined using kappa statistics. RESULTS: Our patients had no adverse reactions to iopanoic acid. The degree of biliary opacification was sufficient to perform three-dimensional and two-dimensional reconstructions in 29 patients (93.5%). Two patients were excluded from statistical analysis because cannulation of the common bile duct during retrograde cholangiography failed. Findings on endoscopic retrograde cholangiography in the remaining 29 patients were the following: choledocholithiasis (n = 14), common bile duct dilatation with no stones (n = 11), and normal bile ducts (n = 4). Sensitivity and specificity of oral-contrast-enhanced CT cholangiography for detection of choledocholithiasis were 92.9% (95% confidence interval [CI], 66.1-99.8%) and 100% (95% CI, 78.2-100%), respectively, for observer 1 and 85.7% (95% CI, 57.2-98.2%) and 100% (95% CI, 78.2-100%), respectively, for observer 2. Interobserver agreement was .92 (excellent). CONCLUSION: Helical CT cholangiography performed after oral administration of iopanoic acid appears promising for diagnosis of choledocholithiasis. |
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Authors:
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J A Soto; S M Velez; J Guzmán |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: AJR. American journal of roentgenology Volume: 172 ISSN: 0361-803X ISO Abbreviation: AJR Am J Roentgenol Publication Date: 1999 Apr |
Date Detail:
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Created Date: 1999-12-17 Completed Date: 1999-12-17 Revised Date: 2008-02-15 |
Medline Journal Info:
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Nlm Unique ID: 7708173 Medline TA: AJR Am J Roentgenol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 943-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology, Universidad de Antioquia, Medellín, Colombia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Oral Adult Aged Aged, 80 and over Cholangiography* Cholangiopancreatography, Endoscopic Retrograde Contrast Media / administration & dosage* Female Gallstones / radiography* Humans Image Processing, Computer-Assisted Iopanoic Acid / administration & dosage, diagnostic use Male Middle Aged Prospective Studies Sensitivity and Specificity Tomography, X-Ray Computed* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 96-83-3/Iopanoic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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