| Choledochal cysts: age of presentation, symptoms, and late complications related to Todani's classification. | |
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MedLine Citation:
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PMID: 12407541 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: The aim of this study was to compare presentation, complications, diagnosis, and treatment of choledochal cysts in pediatric and adult patients. METHODS: Forty-two patients were analyzed after subdivision into 3 groups: group A, less than 2 years (n = 10); group B, 2 to 16 years (n = 11); group C, greater than 16 years (n = 21). RESULTS: The cysts were classified as extrahepatic (n = 33), intrahepatic (n = 5), and combined (n = 4). Seventy-six percent of patients presented with abdominal pain, (20 of 21 group C), and 57% with jaundice, (10 of 10 group A). Cholangiocarcinoma occurred in 6 patients, 4 of whom had previously undergone internal drainage procedures. Excision of the extrahepatic cyst was performed in 27 of 37 patients. Five patients, of whom, 4 had cholangiocarcinoma, were beyond curative treatment at the time of diagnosis. Six patients had died at the closure of this study, 5 of them had carcinoma. CONCLUSIONS: Presenting symptoms are age dependent with jaundice prevailing in children and abdominal pain in adults. In view of the high risk of cholangiocarcinoma, early resection and not internal drainage is the appropriate treatment of extrahepatic cysts. Patients who had undergone internal drainage in the past still should undergo resection of the cyst. |
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Authors:
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J S de Vries; S de Vries; D C Aronson; D K Bosman; E A J Rauws; A Bosma; H A Heij; D J Gouma; T M van Gulik |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Journal of pediatric surgery Volume: 37 ISSN: 1531-5037 ISO Abbreviation: J. Pediatr. Surg. Publication Date: 2002 Nov |
Date Detail:
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Created Date: 2002-10-30 Completed Date: 2002-11-27 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0052631 Medline TA: J Pediatr Surg Country: United States |
Other Details:
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Languages: eng Pagination: 1568-73 Citation Subset: IM |
Copyright Information:
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Copyright 2002, Elsevier Science (USA). All rights reserved. |
Affiliation:
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Department of Surgery, Academic Medical Center and Vrije Universiteit Medical Center, Amsterdam, The Netherlands. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abdominal Pain
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epidemiology* Adolescent Adult Age Distribution Age Factors Bile Duct Neoplasms / epidemiology Bile Ducts, Intrahepatic Case-Control Studies Child Child, Preschool Cholangiocarcinoma / epidemiology Choledochal Cyst / classification, diagnosis*, epidemiology*, therapy Cohort Studies Comorbidity Digestive System Surgical Procedures / adverse effects Drainage Female Follow-Up Studies Humans Infant Jaundice / epidemiology* Liver Neoplasms / epidemiology, secondary Male Netherlands / epidemiology Prevalence Sex Distribution Survival Rate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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