Document Detail

Cholecystokinin, secretin, pancreatic polypeptide in relation to gallbladder dynamics and gastrointestinal interdigestive motility.
MedLine Citation:
PMID:  2373268     Owner:  NLM     Status:  MEDLINE    
Using a combined technique of hepatobiliary scintigraphy and gastrointestinal motility recordings, the changes in blood concentrations of cholecystokinin (CCK), secretin and pancreatic polypeptide (PP) were studied in relation to gastrointestinal motility and gallbladder dynamics in the interdigestive state in 7 healthy male volunteers. No changes in CCK concentration were found in relation to the migrating motor complex (MMC). In 3 subjects a slightly but insignificant elevated secretin level was seen during phase I of the MMC, otherwise no changes were observed. More pronounced fluctuations in PP appeared with significantly higher values during phase III compared to phase II. Values of concentrations of CCK, secretin and PP in periods with gallbladder filling were not significantly different from the values in periods of emptying.
N Qvist; E Oster-Jørgensen; L Rasmussen; S A Pedersen; O Olsen; P Cantor; O B Schaffalitzky de Muckadell
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Digestion     Volume:  45     ISSN:  0012-2823     ISO Abbreviation:  Digestion     Publication Date:  1990  
Date Detail:
Created Date:  1990-08-29     Completed Date:  1990-08-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0150472     Medline TA:  Digestion     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  130-7     Citation Subset:  IM    
Department of Surgical and Medical Gastroenterology, Odense University Hospital, Denmark.
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MeSH Terms
Bile / secretion
Biliary Tract / radionuclide imaging
Cholecystokinin / blood*
Digestion / physiology
Gallbladder / physiology*
Gastrointestinal Motility / physiology*
Imino Acids / diagnostic use
Organotechnetium Compounds / diagnostic use
Pancreatic Polypeptide / blood*
Secretin / blood*
Technetium Tc 99m Lidofenin
Reg. No./Substance:
0/Imino Acids; 0/Organotechnetium Compounds; 0/Technetium Tc 99m Lidofenin; 1393-25-5/Secretin; 59763-91-6/Pancreatic Polypeptide; 9011-97-6/Cholecystokinin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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