Document Detail


Cholecystitis during pregnancy. A case report and brief review of the literature.
MedLine Citation:
PMID:  18225691     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cholecystitis is an inflammation of the gallbladder caused by obstruction of the cystic duct. A gallstone usually causes the obstruction (calculus cholecystitis). However, in some cases the obstruction may be acalculous or caused by sludge. The clinical course of biliary sludge varies, from complete resolution to gallbladder obstruction. This obstruction can result in gallbladder distension and acute cholecystitis. When inflammation occurs it could either be aseptic or bacterial. Biliary disease during pregnancy is relatively rare and occurs mainly during the last trimester. Whether women who are pregnant or have multiple pregnancies are more likely to develop stones or whether they are simply more symptomatic with stones is unknown. We present a 33-year-old obese pregnant woman with fever, moderately elevated bile acids, and leukocytosis in the 28th week of pregnancy. Since need for surgery in these cases is controversial, the patient has been treated conservatively. In our case cholecystitis responded very well to treatment with amoxicillin, with no detrimental effects for mother and child. A healthy child was born at term. In the differential diagnosis of liver function abnormalities during pregnancy, cholelithiasis should be included.
Authors:
C Chloptsios; V Karanasiou; G Ilias; N Kavouras; K Stamatiou; F Lebren
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Clinical and experimental obstetrics & gynecology     Volume:  34     ISSN:  0390-6663     ISO Abbreviation:  Clin Exp Obstet Gynecol     Publication Date:  2007  
Date Detail:
Created Date:  2008-01-29     Completed Date:  2008-02-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7802110     Medline TA:  Clin Exp Obstet Gynecol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  250-1     Citation Subset:  IM    
Affiliation:
Surgery Department, General Hospital of Thebes, Greece.
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MeSH Terms
Descriptor/Qualifier:
Adult
Amoxicillin / therapeutic use
Anti-Bacterial Agents / therapeutic use
Cholagogues and Choleretics / therapeutic use
Cholecystitis, Acute / complications*,  drug therapy
Female
Humans
Pregnancy
Pregnancy Complications*
Pregnancy Outcome
Pregnancy Trimester, Second*
Ursodeoxycholic Acid / therapeutic use
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Cholagogues and Choleretics; 128-13-2/Ursodeoxycholic Acid; 26787-78-0/Amoxicillin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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