Document Detail


Cholangiocarcinoma in sclerosing cholangitis. The role of liver transplantation.
MedLine Citation:
PMID:  2540107     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Our experience with patients who underwent orthotopic liver transplantation for sclerosing cholangitis at the University of Pittsburgh Health Center between March 1980 and March 1988 is reported here. Ten patients had an associated cholangiocarcinoma. Six of these patients died of recurrent, disseminated cancer, usually before one year. One patient died of sepsis, while three are alive and apparently free of tumor four months to almost two years later. Pre-operative identification of a possible cholangiocarcinoma and complete resection are of crucial importance. Adjuvant therapy, especially pre-transplant radiation with a prophylactic purpose is still being evaluated.
Authors:
A C Stieber; I R Marino; S Iwatsuki; T E Starzl
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  International surgery     Volume:  74     ISSN:  0020-8868     ISO Abbreviation:  Int Surg     Publication Date:    1989 Jan-Mar
Date Detail:
Created Date:  1989-06-08     Completed Date:  1989-06-08     Revised Date:  2013-06-12    
Medline Journal Info:
Nlm Unique ID:  0043524     Medline TA:  Int Surg     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  1-3     Citation Subset:  IM    
Affiliation:
Department of Surgery, University of Pittsburgh Health Center, Pennsylvania.
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MeSH Terms
Descriptor/Qualifier:
Adenoma, Bile Duct / complications*
Adult
Bile Duct Neoplasms / complications*
Cholangiography
Cholangitis, Sclerosing / complications,  surgery*
Female
Humans
Liver Transplantation*
Male
Middle Aged
Grant Support
ID/Acronym/Agency:
AM 29961/AM/NIADDK NIH HHS; R01 DK029961-19/DK/NIDDK NIH HHS
Comments/Corrections

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