Document Detail

Choice in a variable environment: effects of d-amphetamine on sensitivity to reinforcement.
MedLine Citation:
PMID:  20188157     Owner:  NLM     Status:  MEDLINE    
Four pigeons responded under a 7-component mixed schedule in which each component arranged a different left:right reinforcer ratio (27:1, 9:1, 3:1, 1:1, 1:3, 1:9, 1:27). Components were unsignaled, and the order within each session was randomly determined. After extensive exposure to these contingencies, effects of a range of doses of d-amphetamine (0.3-5.6mg/kg) on estimates of sensitivity to reinforcement at several levels of analysis were assessed. Under non-drug conditions, the structure of choice was similar to that previously reported under this procedure. That is, responding adjusted within components to the reinforcer ratio in effect (i.e., sensitivity estimates were higher in the 2nd than in the 1st half of components), and individual reinforcers produced "preference pulses" (i.e., each food presentation produced an immediate, local, shift in preference toward the response that just produced food). Although there was a general tendency for d-amphetamine to reduce overall sensitivity to reinforcement, the size of this effect and its reliability varied across pigeons. Further analysis, however, revealed that intermediate d-amphetamine doses consistently reduced sensitivity immediately following reinforcer presentations; that is, these doses consistently attenuated preference pulses.
Andrew M Rodewald; Christine E Hughes; Raymond C Pitts
Related Documents :
3227037 - Different effects of short- and long-term treatment with imipramine on the apomorphine-...
6494297 - Hippocampal stimulation limits performance but does not retard acquisition of food-rein...
16050037 - Effects of reinforcer probability, delay, and response requirements on the choices of r...
11566237 - Three tests of 'anticipatory responding' as an account for induction produced by upcomi...
421457 - Nickel in food: the role of stainless-steel utensils.
24861137 - Uptake and depuration of gold nanoparticles in daphnia magna.
Publication Detail:
Type:  Journal Article     Date:  2010-02-24
Journal Detail:
Title:  Behavioural processes     Volume:  84     ISSN:  1872-8308     ISO Abbreviation:  Behav. Processes     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-19     Completed Date:  2010-07-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7703854     Medline TA:  Behav Processes     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  460-4     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2009 Elsevier B.V. All rights reserved.
University of North Carolina Wilmington, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Central Nervous System Stimulants / administration & dosage,  pharmacology*
Choice Behavior / drug effects*
Dextroamphetamine / administration & dosage,  pharmacology*
Dose-Response Relationship, Drug
Feeding Behavior / drug effects
Reinforcement (Psychology)*
Reinforcement Schedule
Task Performance and Analysis
Reg. No./Substance:
0/Central Nervous System Stimulants; 51-64-9/Dextroamphetamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Triterpenoids from Calophyllum inophyllum and their growth inhibitory effects on human leukemia HL-6...
Next Document:  Identification of post-generation effect of 3, 4- methylenedioxymethamphetamine on the mouse brain b...