Document Detail

Choanal stenosis: an unusual late complication of radiation therapy for nasopharyngeal carcinoma.
MedLine Citation:
PMID:  15794084     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Choanal stenosis, usually a congenital anomaly in children, recently has been recognized as a late complication of radiation therapy (RT) for nasopharyngeal carcinoma (NPC). METHODS: We described the clinical history, preoperative evaluation, surgical management, and postoperative course of a case of acquired choanal stenosis after RT. RESULTS: The patient, a 39-year-old woman, presented with a history of NPC 16 years before presentation that had been successfully treated with RT On presentation, the patient complained of decreased nasal airflow. Bilateral choanal stenosis was confirmed per rigid nasal endoscopy. Transnasal endoscopic repair with mitomycin application was performed, and nasal stents were left in place for 6 weeks. Postoperative endoscopic examination showed patent choanae and a patent nasopharynx without stenosis. The patient continues to have good airflow 20 months postoperatively. CONCLUSION: Choanal stenosis can occur as an unusual complication of RT for NPC secondary to postradiation fibrosis. This is the first report of such a complication in the West.
Peter M Shepard; Steven M Houser
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of rhinology     Volume:  19     ISSN:  1050-6586     ISO Abbreviation:  Am J Rhinol     Publication Date:    2005 Jan-Feb
Date Detail:
Created Date:  2005-03-29     Completed Date:  2005-06-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8807268     Medline TA:  Am J Rhinol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  105-8     Citation Subset:  IM    
Department of Otolaryngology, MetroHealth Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio 44109, USA.
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MeSH Terms
Carcinoma / pathology,  radiotherapy*
Choanal Atresia / etiology*
Follow-Up Studies
Nasal Cavity / pathology,  radiation effects*,  surgery
Nasopharyngeal Neoplasms / pathology,  radiotherapy*
Otorhinolaryngologic Surgical Procedures / methods
Radiation Injuries / etiology*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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