| Chlorpromazine and propranolol extend survival of infant mice inoculated with enterotoxigenic Escherichia coli. | |
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MedLine Citation:
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PMID: 7044258 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Effects of chlorpromazine and propranolol were tested in infant mice model of Enterotoxigenic Escherichia coli diarrhea. Reference strain B41 inoculated orally from 18 h to 48 h after birth causes death of almost all animals in less than 48 h. Both drugs, which are known to reverse submaximal induced secretion by heat-stable toxin in the suckling mouse assay, used as single treatment, were able to extend the survival of mice. |
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Authors:
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A Bertin |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Annales de recherches vétérinaires. Annals of veterinary research Volume: 12 ISSN: 0003-4193 ISO Abbreviation: Ann. Rech. Vet. Publication Date: 1981 |
Date Detail:
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Created Date: 1982-07-22 Completed Date: 1982-07-22 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 1267230 Medline TA: Ann Rech Vet Country: FRANCE |
Other Details:
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Languages: eng Pagination: 137-41 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Oral Animals Chlorpromazine / administration & dosage, therapeutic use* Diarrhea / drug therapy, mortality Escherichia coli Infections / drug therapy*, mortality Injections, Subcutaneous Mice Mice, Inbred Strains Propranolol / administration & dosage, therapeutic use* |
| Chemical | |
Reg. No./Substance:
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50-53-3/Chlorpromazine; 525-66-6/Propranolol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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