Document Detail

Chlorpromazine and frusemide in treatment of acute left-ventricular failure.
MedLine Citation:
PMID:  6103327     Owner:  NLM     Status:  MEDLINE    
Chlorpromazine, a phenothiazine derivative with central and peripheral vasodilating effect, was given intravenously, with frusemide, to five patients with acute pulmonary oedema who did not respond to conventional treatment. Four of the five recovered fully. Chlopromazine seems to be a suitable vasodilator for use in treating acute pulmonary oedema outside intensive-care units, since its use does not require monitoring by invasive techniques.
E Romano; A Gullo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Lancet     Volume:  1     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  1980 May 
Date Detail:
Created Date:  1980-07-26     Completed Date:  1980-07-26     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1000-2     Citation Subset:  AIM; IM    
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MeSH Terms
Acute Disease
Blood Pressure / drug effects
Carbon Dioxide / blood
Chlorpromazine / administration & dosage,  therapeutic use*
Drug Therapy, Combination
Furosemide / administration & dosage,  therapeutic use*
Heart Failure / drug therapy*
Heart Rate / drug effects
Heart Ventricles / drug effects
Hydrogen-Ion Concentration
Injections, Intravenous
Middle Aged
Pulmonary Edema / drug therapy*,  physiopathology
Respiration / drug effects
Vasodilator Agents
Reg. No./Substance:
0/Vasodilator Agents; 124-38-9/Carbon Dioxide; 50-53-3/Chlorpromazine; 54-31-9/Furosemide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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