Document Detail


Chloroquine retinopathy. Is fluorescein angiography necessary?
MedLine Citation:
PMID:  4047606     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Color fundus photographs and corresponding fluorescein angiograms from 83 patients suspected of having chloroquine retinopathy were reviewed in a retrospective masked study to determine the relative sensitivity of these two photographic methods in the diagnosis of retinal toxicity. We identified retinal toxicity on both color photographs and fluorescein angiograms in 7.6% of cases, on the color photographs but not on the corresponding angiograms in 6.1% of cases, and on the fluorescein angiograms but not on the color photographs in 1.5% of cases. Fluorescein angiography may not be as sensitive as color fundus photography (or ophthalmoscopy) in the diagnosis of chloroquine retinopathy.
Authors:
A F Cruess; A P Schachat; J Nicholl; J J Augsburger
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Ophthalmology     Volume:  92     ISSN:  0161-6420     ISO Abbreviation:  Ophthalmology     Publication Date:  1985 Aug 
Date Detail:
Created Date:  1985-11-20     Completed Date:  1985-11-20     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7802443     Medline TA:  Ophthalmology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1127-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Chloroquine / adverse effects*
Evaluation Studies as Topic
Fluorescein Angiography*
Fundus Oculi
Humans
Photography
Retinal Diseases / chemically induced*,  diagnosis,  pathology
Chemical
Reg. No./Substance:
54-05-7/Chloroquine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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