Document Detail

Chloral hydrate poisoning: its mechanism and therapy.
MedLine Citation:
PMID:  505984     Owner:  NLM     Status:  MEDLINE    
Chloral hydrate is a dangerous hypnotic drug to prescribe. Lethal dose can be a small as 4 gm. Nowadays the effects on the circulatory system are most dangerous. Which metabolite is responsible remains to be investigated. Haemoperfusion seems to be best method of lowering plasma levels of the metabolites, although the clearance of trichloroacetic acid is considered lower than of trichloroethanol.
M Gerretsen; G de Groot; A N van Heijst; R A Maes
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Veterinary and human toxicology     Volume:  21 Suppl     ISSN:  0145-6296     ISO Abbreviation:  Vet Hum Toxicol     Publication Date:  1979  
Date Detail:
Created Date:  1980-01-24     Completed Date:  1980-01-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7704194     Medline TA:  Vet Hum Toxicol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  53-6     Citation Subset:  IM    
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MeSH Terms
Chloral Hydrate / metabolism,  poisoning*
Reg. No./Substance:
302-17-0/Chloral Hydrate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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