Document Detail

Chlamydia public health programs and the epidemiology of pelvic inflammatory disease and ectopic pregnancy.
MedLine Citation:
PMID:  23100568     Owner:  NLM     Status:  Publisher    
Background. Many countries have witnessed a disturbing increase in Chlamydia trachomatis cases despite enhanced control programs. Since the goal of Chlamydia control is to prevent reproductive complications such as pelvic inflammatory disease and ectopic pregnancy, an understanding of recent trends in these conditions is needed to fully evaluate the effect of control efforts.Methods. We analyzed two provincial, comprehensive health services administrative databases (encompassing hospitalizations and all physician-delivered services) for pelvic inflammatory disease and ectopic pregnancy trends from 1992-2009 in women of reproductive age in British Columbia. Trends were compared to provincial Chlamydia surveillance data by time series analysis using the cross-correlation function method and Granger-causality testing.Results. Chlamydia cases substantially increased from 1992-2009. Inpatient, outpatient and total pelvic inflammatory disease and ectopic pregnancy diagnoses declined from 1992-2003. After 2003, pelvic inflammatory disease rates continued to fall while ectopic pregnancy rates significantly increased. The male Chlamydia urethritis rate increased from 39.4 to 173.6/100,000 from 1996-2009.Conclusions. In the context of increasing Chlamydia rates, the reproductive complications of Chlamydia infection in women are declining overall. A recent increase in ectopic pregnancies is cause for concern.
Michael L Rekart; Mark Gilbert; Rafael Meza; Paul H Kim; Michael Chang; Deborah M Money; Robert C Brunham
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-24
Journal Detail:
Title:  The Journal of infectious diseases     Volume:  -     ISSN:  1537-6613     ISO Abbreviation:  J. Infect. Dis.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0413675     Medline TA:  J Infect Dis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
School of Population and Public Health, University of British Columbia, Vancouver V6T 1Z3, Canada.
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