Document Detail


Chlamydia pneumoniae antibody response in patients with acute myocardial infarction and their follow-up.
MedLine Citation:
PMID:  9453516     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
RESULTS: High titers of C. pneumoniae microimmunofluorescence antibodies were found in 89.65% of the AMI group and in 25% of the HCM group (p = 0.0000065). Immunoglobulin A-microimmunofluorescence was 51.72% in the AMI group and 20.83% in the HCM group (p = 0.0042). Immunoglobulin G and immunoglobulin A antilipopolysoccharide titers were 65.51% and 62.60% in the AMI group and 20.83% in the HCM group, respectively (p = 0.006). High concentrations of interleukin-6 were found in 86.20% of our AMI group (p value = 54.38 pg/ml) when compared with the control group. A good correlation between interleukin-6 levels and immunoglobulin A-lipopolysaccharide titers (r = 0.658) was found.
CONCLUSION: The presence of a high prevalence rate and high titers of immunoglobulin G and immunoglobulin A-specific anti-C. pneumoniae antibodies in AMI at admission demonstrated the presence of a specific anti-C. pneumoniae immunization in the AMI population.
Authors:
S Mazzoli; N Tofani; A Fantini; F Semplici; F Bandini; A Salvi; R Vergassola
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  135     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1998 Jan 
Date Detail:
Created Date:  1998-02-10     Completed Date:  1998-02-10     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  15-20     Citation Subset:  AIM; IM    
Affiliation:
Sexually Transmitted Diseases Centre, Infectious Diseases Unit, S.M. Annunziata Hospital, Florence, Italy.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Antibodies, Viral / blood*
Case-Control Studies
Chlamydophila pneumoniae / immunology*
Enzyme-Linked Immunosorbent Assay
Female
Fluorescent Antibody Technique
Follow-Up Studies
Humans
Immunoglobulin A / blood
Immunoglobulin G / blood
Interleukin-6 / blood
Male
Middle Aged
Myocardial Infarction / immunology,  microbiology*
Prevalence
Risk Factors
Chemical
Reg. No./Substance:
0/Antibodies, Viral; 0/Immunoglobulin A; 0/Immunoglobulin G; 0/Interleukin-6

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