Document Detail


Chlamydia pneumoniae IgG serological status and venous thromboembolism: a cross-sectional hospital based study.
MedLine Citation:
PMID:  15614169     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To search for a link between Chlamydia pneumoniae serological status and venous thromboembolic disease. METHODS: From March 1992 to October 1999, we conducted a cross-sectional hospital-based study of consecutive unselected outpatients referred to us for clinical suspicion of venous thromboembolism. We compared the Chlamydia pneumoniae serological status with respectively, the venous thromboembolism, the deep vein thrombosis and the proximal deep vein thrombosis status. RESULTS: Among 1193 patients registered for suspected venous thromboembolism, 1010 samples were available (499 negative and 511 positive patients for venous thromboembolism). Seventy-nine patients were Chlamydia pneumoniae positive. Our work failed to demonstrate any clear association between Chlamydia pneumoniae and venous thromboembolism status. Nevertheless, we identified a statistical difference regarding Chlamydia pneumoniae seropositivity and proximal vein thrombosis status (adjusted odds ratio of 1.70, CI95%: 1.05 to 2.77). CONCLUSION: The presence of Chlamydia pneumoniae antibodies might be a minor risk factor for venous thrombosis.
Authors:
L de Saint Martin; E Pasquier; F Betsou; A Tran; F Couturaud; J Orfila
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Presse médicale (Paris, France : 1983)     Volume:  33     ISSN:  0755-4982     ISO Abbreviation:  Presse Med     Publication Date:  2004 Dec 
Date Detail:
Created Date:  2004-12-22     Completed Date:  2005-02-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8302490     Medline TA:  Presse Med     Country:  France    
Other Details:
Languages:  eng     Pagination:  1493-6     Citation Subset:  IM    
Affiliation:
Internal Medicine and Chest Disease Department, University Hospital of Brest, France. luc.desaintmartin@chu-brest.fr
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MeSH Terms
Descriptor/Qualifier:
Aged
Antibodies, Bacterial / blood
Chlamydophila Infections / blood,  epidemiology*,  immunology
Chlamydophila pneumoniae / immunology*,  isolation & purification
Cross-Sectional Studies
Female
France / epidemiology
Humans
Immunoglobulin G / blood*
Male
Middle Aged
Seroepidemiologic Studies
Venous Thrombosis / epidemiology*
Chemical
Reg. No./Substance:
0/Antibodies, Bacterial; 0/Immunoglobulin G

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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