Document Detail

Chitosan, the marine functional food, is a potent adsorbent of humic acid.
MedLine Citation:
PMID:  22363235     Owner:  NLM     Status:  MEDLINE    
Chitosan is prepared by the deacetylation of chitin, the second-most abundant biopolymer in nature, and has applicability in the removal of dyes, heavy metals and radioactive waste for pollution control. In weight-reduction remedies, chitosan is used to form hydrogels with lipids and to depress the intestinal absorption of lipids. In this study, an experimental method was implemented to simulate the effect of chitosan on the adsorption of humic acid in the gastrointestinal tract. The adsorption capacity of chitosan was measured by its adsorption isotherm and analyzed using the Langmuir equation. The results showed that 3.3 grams of humic acid was absorbed by 1 gram of chitosan. The adsorption capacity of chitosan was much greater than that of chitin, diethylaminoethyl-cellulose or activated charcoal. Cellulose and carboxymethyl-cellulose, a cellulose derivative with a negative charge, could not adsorb humic acid in the gastrointestinal tract. This result suggests that chitosan entraps humic acid because of its positive charge.
Jeen-Kuan Chen; Chao-Hsien Yeh; Lian-Chen Wang; Tzong-Horng Liou; Chia-Rui Shen; Chao-Lin Liu
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2011-11-28
Journal Detail:
Title:  Marine drugs     Volume:  9     ISSN:  1660-3397     ISO Abbreviation:  Mar Drugs     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2012-02-24     Completed Date:  2012-06-28     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  101213729     Medline TA:  Mar Drugs     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  2488-98     Citation Subset:  IM    
Environment and Biotechnology Department, Refining and Manufacturing Research Institute, CPC Corporation, Chia-Yi, Taiwan.
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MeSH Terms
Chitosan / chemistry*
Functional Food*
Humic Substances*
Hydrogen-Ion Concentration
Reg. No./Substance:
0/Humic Substances; 9012-76-4/Chitosan

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