Document Detail

Chitosan and fish collagen as biomaterials for regenerative medicine.
MedLine Citation:
PMID:  22361182     Owner:  NLM     Status:  In-Data-Review    
This chapter focuses and reviews on the characteristics and biomedical application of chitosan and collagen from marine products and advantages and disadvantages of regeneration medicine. The understanding of the production processes of chitosan and collagen and the conformation of these biomaterials are indispensable for promoting the theoretical and practical availability. The initial inflammatory reactions associated with chitosan application to hard and soft tissues need to be controlled before it can be considered for clinical application as scaffold. Further, as chitosan takes too long for biodegradation in vivo, generally it is not suitable for the scaffold for degenerative medicine in especially dental pulp tissue. The collagen extract from the scales of tropical fish has been reported to have a degeneration temperature of 35°C. The properties of biocompatibility and biodegradation of fish atelocollagen are suitable for the scaffold in regenerative medicine.
Yoshihiko Hayashi; Shizuka Yamada; Kajiro Yanagi Guchi; Zenya Koyama; Takeshi Ikeda
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Advances in food and nutrition research     Volume:  65     ISSN:  1043-4526     ISO Abbreviation:  Adv. Food Nutr. Res.     Publication Date:  2012  
Date Detail:
Created Date:  2012-02-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9001271     Medline TA:  Adv Food Nutr Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  107-20     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Department of Cariology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
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