| Chiroptical study of α-aliphatic amino acid films in the vacuum ultraviolet region. | |
| | |
MedLine Citation:
|
PMID: 20958008 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
A series of natural circular dichroism (CD) and absorption spectra for films of α-aliphatic amino acids--such as alanine, aminobutyric acid, norvaline, norleucine, valine, leucine, and isoleucine--in the vacuum ultraviolet (VUV) region were observed with the absolute values of optical constants at the undulator-based CD beamline TERAS BL5. Preliminary predictions of some CD spectra were also performed, based on quantum-chemical calculations using the crystal structure. Although the absorption spectra show similar features to each other, significant differences between the CD spectra were found, especially in the 7-8 eV region. The CD spectra of aliphatic amino acids with branched alkyl groups in the side-chain--such as valine, leucine, and isoleucine--exhibit strong negative CD peaks in this energy region. In contrast, the corresponding CD peaks were weak or absent in the spectra of amino acids with straight alkyl groups. Our simple calculation, and the absorption spectra of alkanes, suggest that this difference partly originates from the contribution of the alkyl group. Clear discrepancies between the CD spectra of these amino acids in solutions and those in the solid state were also observed; this is probably caused by the different molecular structures in each state. Our results clearly indicated that CD spectra in the VUV region were very sensitive to the conformations of chiral molecules. |
| | |
Authors:
|
Masahito Tanaka; Kazutoshi Yagi-Watanabe; Fusae Kaneko; Kazumichi Nakagawa |
Related Documents
:
|
1452948 - Plasma amino acid responses of trained athletes to two successive exhaustion trials wit... 14086108 - Effect of alanine and threonine on the synthesis of serine by leuconostoc mesenteroides. 6140798 - Metabolism of amino acids in ascaridia galli: transamination. 7305998 - The accumulation of amino acids by mouse ascites-tumour cells. dependence on but lack o... 2868908 - 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) administration to c57-black mice le... 10933888 - Essential role of trehalose in the synthesis and subsequent metabolism of corynomycolic... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: The journal of physical chemistry. A Volume: 114 ISSN: 1520-5215 ISO Abbreviation: J Phys Chem A Publication Date: 2010 Nov |
Date Detail:
|
Created Date: 2010-11-04 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9890903 Medline TA: J Phys Chem A Country: United States |
Other Details:
|
Languages: eng Pagination: 11928-32 Citation Subset: IM |
Affiliation:
|
Research Institute of Instrumentation Frontier, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba Central 2, Umezono 1-1-1, Tsukuba, Ibaraki 305-8568, Japan. masahito-tanaka@aist.go.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Long-range migration of a water molecule to catalyze a tautomerization in photoionization of the hyd...
Next Document: Structural, electronic, and vibrational properties of amino-adamantane and rimantadine isomers.