Document Detail

Chiral ligand-exchange chromatography of amino acids using porous graphitic carbon coated with a dinaphthyl derivative of neamine.
MedLine Citation:
PMID:  18998115     Owner:  NLM     Status:  MEDLINE    
In this paper, we describe the preparation and the evaluation of a porous graphitic carbon (PGC) column coated with a new dinaphthyl derivative of neamine for chiral ligand-exchange (LE) chromatography. It was shown that the graphitic surface/dinaphthyl anchor system efficiently (1.15 micromol/m(2)) and stably (three months of intensive use) adsorbs the neamine template onto the chromatographic support. The resulting coated PGC stationary phase showed appreciable LE-based enantioselective properties towards several native amino acids.
Mustapha Zaher; Corinne Ravelet; Isabelle Baussanne; Anne Ravel; Catherine Grosset; Jean-Luc Décout; Eric Peyrin
Related Documents :
20503935 - Hplc and tlc enantioseparation of the nitro-positioned aryloxysubstituted aminopropanols.
19277955 - Hplc determination of acidic d-amino acids and their n-methyl derivatives in biological...
14582625 - Separation of phytic acid and other related inositol phosphates by high-performance ion...
7540365 - Analysis of phosphorylhydroxyamino acids present in hydrolyzed cell extracts using dabs...
8841385 - In vivo incorporation of lipoic acid enantiomers and homologues in the pyruvate dehydro...
3245835 - Aging influence on delta-6-desaturase activity and fatty acid composition of rat liver ...
Publication Detail:
Type:  Journal Article     Date:  2008-11-09
Journal Detail:
Title:  Analytical and bioanalytical chemistry     Volume:  393     ISSN:  1618-2650     ISO Abbreviation:  Anal Bioanal Chem     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2008-12-19     Completed Date:  2009-02-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101134327     Medline TA:  Anal Bioanal Chem     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  655-60     Citation Subset:  IM    
Département de Pharmacochimie Moléculaire UMR 5063 CNRS, Institut de Chimie Moléculaire de Grenoble FR 2607, Université Grenoble I (Joseph Fourier), UFR de Pharmacie, 38041, Grenoble cedex 9, France.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Amino Acids / analysis*
Chromatography, High Pressure Liquid / methods*
Framycetin / analogs & derivatives*,  chemical synthesis,  chemistry
Graphite / chemistry*
Molecular Structure
Surface Properties
Time Factors
Reg. No./Substance:
0/3',6-di-O-2-methylnaphthalene-neamine; 0/Amino Acids; 0/Ligands; 119-04-0/Framycetin; 7782-42-5/Graphite

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Effects of allopregnanolone on the reinstatement of cocaine-seeking behavior in male and female rats...
Next Document:  Characterization of surface-confined ionic liquid stationary phases: impact of cation and anion iden...