Document Detail


A Chinese adolescent girl with Fechtner-like syndrome.
MedLine Citation:
PMID:  9686669     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe a 15-y-old girl with Fechtner-like syndrome, who is the first Chinese reported to have this rare syndrome. She presented with left homonymous hemianopia and neuroimaging revealed haemorrhage in both parietal and occipital lobes. Peripheral blood smear showed macrothrombocytopenia and intracytoplasmic inclusion bodies inside leucocytes. Thrombocytopenia and proteinuria responded to intravenous immunoglobulin and pulsed methylprednisolone. This case illustrates that life-threatening haemorrhage can occur in patients with Fechtner syndrome. Although there was no effective treatment reported in the literature, high dose steroid and immunoglobulin seemed to be useful in our patient. Our patient also had nephritic-nephrotic syndrome with renal insufficiency, which is unusual in adolescent female patients.
Authors:
T F Leung; W C Tsoi; C K Li; K W Chik; M M Shing; P M Yuen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  87     ISSN:  0803-5253     ISO Abbreviation:  Acta Paediatr.     Publication Date:  1998 Jun 
Date Detail:
Created Date:  1998-10-06     Completed Date:  1998-10-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  705-7     Citation Subset:  IM    
Affiliation:
Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Cataract* / diagnosis
Cerebral Hemorrhage* / diagnosis
China / ethnology
Cytoplasm / ultrastructure
Deafness* / diagnosis
Diagnosis, Differential
Female
Glaucoma* / diagnosis
Hong Kong
Humans
Leukocytes / ultrastructure
Nephritis* / diagnosis
Purpura, Thrombocytopenic, Idiopathic* / diagnosis
Syndrome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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