| Childhood non-Hodgkin lymphoma presenting as hemophagocytic syndrome. | |
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MedLine Citation:
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PMID: 11787866 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An 8-year-old girl with a progressive systemic hemopagocytic syndrome was found to have non-Hodgkin lymphoma (NHL) after multiple nondiagnostic biopsies. Routine histochemistry and flow cytometry demonstrated this to be a peripheral T-cell process and cytogenetics identified a t(2;5)(p23;q35). An extensive evaluation for an infectious agent failed to identify a pathogen. Treatment according to a standard lymphoma protocol produced a rapid response and the girl remains in remission without evidence of hemophagocytic syndrome 18 months from diagnosis. In children with systenic hemophagocytosis, a diagnosis of NHL should be aggressively pursued. |
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Authors:
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Julie Blatt; Brent Weston; Tom Belhorn; Harvey Hamrick; Diane Maia |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Pediatric hematology and oncology Volume: 19 ISSN: 0888-0018 ISO Abbreviation: Pediatr Hematol Oncol Publication Date: 2002 Jan-Feb |
Date Detail:
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Created Date: 2002-01-11 Completed Date: 2002-06-24 Revised Date: 2006-04-24 |
Medline Journal Info:
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Nlm Unique ID: 8700164 Medline TA: Pediatr Hematol Oncol Country: England |
Other Details:
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Languages: eng Pagination: 45-9 Citation Subset: IM |
Affiliation:
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Division of Pediatric Hematolotv-Oncology, University of North Carolina, Chapel Hill 27599, USA. jblat@med.unc.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Antineoplastic Combined Chemotherapy Protocols
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therapeutic use Child Diagnosis, Differential Female Histiocytosis, Non-Langerhans-Cell / diagnosis*, drug therapy Humans Lymph Nodes / pathology Lymphoma, Non-Hodgkin / diagnosis*, drug therapy Prognosis Serologic Tests Syndrome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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