Document Detail


Childhood mesial temporal sclerosis.
MedLine Citation:
PMID:  16948937     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The prevalence and clinical characteristics of mesial temporal sclerosis have not been well studied in children. All brain magnetic resonance imaging (MRI) reports of children less than 14 years of age were reviewed from two tertiary institutions. A 52-month period from one institution and a 37-month period from the other were reviewed. All reports of definite or possible mesial temporal sclerosis were noted. These patients' MRIs were then reviewed to confirm the MRI diagnostic criteria of mesial temporal sclerosis. The charts of the patients who satisfied these criteria were reviewed in detail. Three thousand one hundred brain MRI reports were reviewed. Twenty-six reports of mesial temporal sclerosis were found. Twenty-four of the 26 films satisfied the criteria of mesial temporal sclerosis by MRI after the films were reviewed. The prevalence among all pediatric brain MRI studies was 0.77%. All patients had presented with seizures, that is, there were no "incidental" findings of mesial temporal sclerosis. Four patients had a history of febrile seizures. Mesial temporal sclerosis is an uncommon finding in children, but when it occurs, it is always associated with epilepsy. Asymptomatic mesial temporal sclerosis or mesial temporal sclerosis not associated with a seizure disorder did not occur in our series. Febrile seizures can occur in association with mesial temporal sclerosis presenting in childhood.
Authors:
Yu-tze Ng; Amy L McGregor; Dawn C Duane; Heidi K Jahnke; C Roger Bird; James W Wheless
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of child neurology     Volume:  21     ISSN:  0883-0738     ISO Abbreviation:  J. Child Neurol.     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-09-04     Completed Date:  2006-11-09     Revised Date:  2010-06-17    
Medline Journal Info:
Nlm Unique ID:  8606714     Medline TA:  J Child Neurol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  512-7     Citation Subset:  IM    
Affiliation:
Division of Child Neurology, St. Joseph's Hospital and Children's Health Center at Barrow Neurological Institute, 500 West Thomas Road, Phoenix, AZ 85013, USA. y2ng@chw.edu
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MeSH Terms
Descriptor/Qualifier:
Brain Diseases / epidemiology*,  pathology*,  physiopathology
Child
Child, Preschool
Electroencephalography
Female
Humans
Infant
Magnetic Resonance Imaging
Male
Prevalence
Retrospective Studies
Sclerosis
Seizures / etiology,  physiopathology
Temporal Lobe / pathology*,  physiopathology
Comments/Corrections
Comment In:
Epilepsy Curr. 2007 Jul-Aug;7(4):101-2   [PMID:  17694167 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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