| Childhood hardship, maternal smoking, and birth outcomes: a prospective cohort study. | |
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MedLine Citation:
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PMID: 20530303 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To determine the association between type, chronicity, and severity of childhood hardships and smoking status during pregnancy, preterm birth (PTB), and low birth weight (LBW). DESIGN: Prospective cohort study. SETTING: The National Child Development Study, a nationally representative study of births in Great Britain in 1958. PARTICIPANTS: Four thousand eight-hundred sixty-five women with at least 1 singleton live birth. MAIN EXPOSURES: Hardship during childhood, indicated by several variables, including financial/structural hardship, lack of parental interest in education, family dysfunction, violence/mental health issues, and family structure. MAIN OUTCOME MEASURES: Smoking in pregnancy, LBW, and PTB. RESULTS: A consistent and graded association was seen between all types of childhood hardships and smoking status during pregnancy (odds ratio [OR] for 4 or more hardships, 2.02; 95% confidence interval [CI], 1.58-2.58; P < .001 for all comparisons). Most hardships were also associated with risk of LBW and PTB, with associations between number of hardships and both outcomes persisting after controlling for smoking status and adult social class (for LBW, OR, 1.51; 95% CI, 1.10-2.06; for PTB, OR, 1.44; 95% CI, 1.08-1.92). CONCLUSION: Childhood hardships have an enduring impact on future pregnancy outcomes, in part through their association with smoking during pregnancy and adult socioeconomic position. |
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Authors:
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Emily W Harville; Renée Boynton-Jarrett; Chris Power; Elina Hyppönen |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Archives of pediatrics & adolescent medicine Volume: 164 ISSN: 1538-3628 ISO Abbreviation: Arch Pediatr Adolesc Med Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-06-09 Completed Date: 2010-08-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9422751 Medline TA: Arch Pediatr Adolesc Med Country: United States |
Other Details:
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Languages: eng Pagination: 533-9 Citation Subset: AIM; IM |
Affiliation:
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Tulane University, New Orleans, Louisiana, USA. harville@tulane.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Child Domestic Violence Family Relations Female Great Britain / epidemiology Humans Infant, Low Birth Weight* Infant, Newborn Longitudinal Studies Mothers Pregnancy Pregnancy Outcome* Premature Birth / epidemiology*, etiology Prospective Studies Smoking / epidemiology* Social Class Socioeconomic Factors |
| Grant Support | |
ID/Acronym/Agency:
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K12 HD043444/HD/NICHD NIH HHS; K12HD043451/HD/NICHD NIH HHS; //Department of Health; //Medical Research Council |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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