| Childhood Behçet's disease: clinical features and comparison with adult-onset disease. | |
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MedLine Citation:
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PMID: 10371286 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To study the clinical spectrum of Behçet's disease (BD) in childhood, in comparison to adult-onset disease. METHODS: Nineteen children, who fulfilled disease criteria up to the age of 16 yr, were studied. The results were compared to those of 34 adult patients with BD. An activity index and severity score were calculated for both study groups. RESULTS: The mean age of disease onset was 6.9+/-3.9 yr, similar ages of onset were found in males and females. The clinical spectrum of childhood BD resembled that of adult disease; however, the prevalence of certain manifestations was different between children and adults. Children with BD had significantly less genital ulcers, less vascular thromboses and more non-specific gastrointestinal symptoms, as well as central nervous system involvement and arthralgia. A relatively high prevalence of uveitis was found in childhood BD. The activity index and severity score were significantly lower in children than in adults. CONCLUSION: Our results point to a similar systemic expression of BD in children and adults; however, the disease seems to run a less severe course in children. |
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Authors:
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I Krause; Y Uziel; D Guedj; M Mukamel; L Harel; Y Molad; A Weinberger |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Rheumatology (Oxford, England) Volume: 38 ISSN: 1462-0324 ISO Abbreviation: Rheumatology (Oxford) Publication Date: 1999 May |
Date Detail:
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Created Date: 1999-06-24 Completed Date: 1999-06-24 Revised Date: 2007-09-06 |
Medline Journal Info:
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Nlm Unique ID: 100883501 Medline TA: Rheumatology (Oxford) Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 457-62 Citation Subset: AIM; IM |
Affiliation:
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Rheumatology Unit, Rabin Medical Centre, Beilinson Campus, Petah-Tiqva, Israel. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Age Distribution Age of Onset Behcet Syndrome / diagnosis*, epidemiology Child Child, Preschool Female Humans Male Prevalence Severity of Illness Index* |
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