| [Childhood cutaneous granular cell tumor: Case report]. | |
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MedLine Citation:
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PMID: 22451294 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Granular cell tumors (GCT) are benign neoplasms of distinctive differentiation when observed by light microscopy, which are characterized by the presence of cells with abundant granular eosinophilic cytoplasm. Reports in children are extremely rare. An 11-year-old male patient presented with a nodule after six months of evolution, which progressively increased in size, asymptomatic, localized on the back. Exploration revealed an oval nodule, 1.5 cm in diameter, movile, nonadherent, and painless. Histological study revealed a non-encapsulated tumorous lesion formed by large cells, organized in clusters, of abundant cytoplasm containing eosinophilic granules and small, centrally located nuclei. Immunohistochemical study demonstrated the presence of S100. Treatment indicated was local conservative surgical excision. We emphasize the need to biopsy persistent ulcerated solitary nodules, for diagnostic accuracy, highlighting the importance of histopathology because clinical diagnosis is difficult and almost never we think about it, unless the tumor arises on the tongue. |
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Authors:
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Beatriz Di Martino Ortiz; Romina Contreras; Lourdes Rodríguez Oviedo; Gladys Argüello; Mirtha Rodríguez; Oilda Knopfelmacher; Lourdes Bolla |
Publication Detail:
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Type: English Abstract; Journal Article |
Journal Detail:
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Title: Archivos argentinos de pediatría Volume: 110 ISSN: 1668-3501 ISO Abbreviation: Arch Argent Pediatr Publication Date: 2012 Apr |
Date Detail:
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Created Date: 2012-03-27 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372460 Medline TA: Arch Argent Pediatr Country: Argentina |
Other Details:
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Languages: spa Pagination: e17-20 Citation Subset: IM |
Affiliation:
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Cátedra de Dermatología, Hospital de Clínicas, Universidad Nacional de Asunción, Paraguay. |
Vernacular Title:
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Tumor cutáneo de células granulares en la infancia: Presentación de un caso. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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