Document Detail


Childhood cholesterol disorders: the iceberg base or nondisease?
MedLine Citation:
PMID:  22391258     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Pediatric cholesterol disorders are common, affecting 1 in 5 adolescents, although most are mild or moderate abnormalities. Because cholesterol values during childhood are moderately predictive of adult cholesterol levels, and are associated with atherosclerosis by pathology and by vascular testing, and because familial hyperlipidemias are associated with early cardiovascular events, cholesterol screening is recommended during childhood. Identified lipid abnormalities are an indication for lifestyle improvement and, in rare cases, pharmacotherapy. However, many gaps in the pediatric knowledge base remain about the benefits and risk, the optimal method for lipid screening, and about appropriate indications for pharmacotherapy.
Authors:
Sarah D de Ferranti
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Medical clinics of North America     Volume:  96     ISSN:  1557-9859     ISO Abbreviation:  Med. Clin. North Am.     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-03-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985236R     Medline TA:  Med Clin North Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  141-54     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Affiliation:
Department of Cardiology, Children's Hospital Boston, 300 Longwood Avenue, FA607, Boston, MA 02115, USA.
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