Document Detail


Childhood carcinoid tumors: description of a case series in a Brazilian cancer center.
MedLine Citation:
PMID:  16612458     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
CONTEXT AND OBJECTIVE: Carcinoid tumors are very rare both in children and adults. About 85% of these tumors develop in the gastrointestinal tract. The objective of the present study was to describe our experience with children treated of carcinoid tumors, and investigate the frequency morphological findings and results. DESIGN AND SETTING: Report on case series, at the Department of Pediatrics of Centro de Tratamento e Pesquisa Hospital do Câncer, São Paulo. METHODS: This was a retrospective analysis of clinical pathological data and outcomes among children (< 18 years old) with carcinoid tumors admitted from January 1, 1990, to December 31, 2001. RESULTS: Nine patients (mean age 12.2 years) were included: six girls and three boys (2:1), all of them Caucasian. In eight cases (89%), the primary tumor site was the appendix and in one (11%) it was the left bronchus. For those with primary tumor in the appendix, the main complaint was abdominal pain, which led to appendectomy. Only one patient underwent right hemicolectomy due to tumor extension into the serosa. The patient with bronchial tumor underwent left pneumonectomy. All patients had localized disease and are alive and free of disease. They have had follow-ups lasting from 1 to 11 years (mean of 3.5 years). CONCLUSION: Although the majority of carcinoid tumors arise from the appendix, these tumors can also occur in other primary sites. Surgical resection at an early stage allows for good prognosis without the need for any adjuvant treatment.
Authors:
Gustavo Ribeiro Neves; Paulo Chapchap; Simone Treiger Sredni; Cristiano Ribeiro Viana; Wellington Luiz Mendes
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Publication Detail:
Type:  Journal Article     Date:  2006-04-03
Journal Detail:
Title:  São Paulo medical journal = Revista paulista de medicina     Volume:  124     ISSN:  1516-3180     ISO Abbreviation:  Sao Paulo Med J     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2006-04-13     Completed Date:  2006-10-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100897261     Medline TA:  Sao Paulo Med J     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  21-5     Citation Subset:  IM    
Affiliation:
Centro de Tratamento e Pesquisa, Hospital do Câncer A. C. Camargo, São Paulo, Brazil.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Appendiceal Neoplasms / pathology*,  therapy
Brazil
Carcinoid Tumor / pathology*,  therapy
Child
Child, Preschool
Female
Follow-Up Studies
Humans
Immunohistochemistry
Male
Neoplasm Invasiveness
Retrospective Studies
Sex Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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