| Childhood Rubella Encephalitis: Diagnosis, Management, and Outcome. | |
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MedLine Citation:
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PMID: 23275435 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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We to report clinical biological and radiologic features of rubella encephalitis in childhood and assess its prognostic impact. Our retrospective study was conducted in an intensive care unit of a university hospital in Sfax, Tunisia. Twenty-one children (age range, 1-15 years) were included. Median age was 9 years (lower and upper quartiles, 7-11 years). On admission, generalized maculopapular eruption was found in 17 cases (81%). Median Glasgow Coma Scale score was 7 (lower and upper quartiles, 7-8). Twenty patients (95.2%) experienced at least 1 episode of seizures. Sixteen patients (76.2%) developed a status epilepticus. The result for enzyme-linked immunosorbent assay detecting anti-rubella immunoglobulin (M) was positive in the serum and in the cerebrospinal fluid samples for all our patients. Magnetic resonance imaging (MRI) of the brain was performed on admission for 3 patients (14.3%) and within a median of 4 days (lower and upper quartiles, 2-6 days) for 8 patients. The test was normal in 6 cases. Two deaths were recorded (9.5%). Survivors had no neurological sequelae 6 months after intensive care unit discharge. |
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Authors:
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Anis Chaari; Mabrouk Bahloul; Lamia Berrajah; Sahar Ben Kahla; Nourhene Gharbi; Hela Karray; Mounir Bouaziz |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-12-28 |
Journal Detail:
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Title: Journal of child neurology Volume: - ISSN: 1708-8283 ISO Abbreviation: J. Child Neurol. Publication Date: 2012 Dec |
Date Detail:
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Created Date: 2012-12-31 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8606714 Medline TA: J Child Neurol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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1Department of Intensive Care, Habib Bourguiba University Hospital, Sfax, Tunisia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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