| Childhood Growth and Adult Hypertension in a Population of High Birth Weight. | |
| | |
MedLine Citation:
|
PMID: 21576624 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Low birth weight has consistently been associated with increased adult blood pressure. The relative importance of childhood growth is, however, less well established. This study examined sex-specific associations between childhood growth and adult blood pressure in 2120 subjects born from 1921 to 1935 in Reykjavik who were recruited into a longitudinal study in 1967-1991. Size at birth and growth at regular intervals between 8 and 13 years were collected from national archives. Hypertensive males did not differ from normotensive males at birth but were increasingly taller and of higher body mass index between 8 and 13 years. No differences in adult height were observed between hypertensive and normotensive males. For boys, growth-velocity (change in growth per year) for body mass index and height between 8 to 13 years was positively associated (P<0.05) with adult blood pressure. The association for body mass index-velocity was fully accounted for by concurrent body size, whereas height-velocity was independent of birth weight and concurrent body size. Males in the highest compared with the lowest tertile in the height-velocity distribution had 66% increased risks of hypertension (95% CI: 15% to 139% increased risks of hypertension) corresponding with 5.0 mm Hg increase (95% CI: 1.5 to 8.5 mm Hg increase) and 3.1 mm Hg increase (95% CI: 1.1 to 5.0 mm Hg increase) in systolic and diastolic blood pressures, respectively. Hypertensive females weighed less at birth but did not differ markedly from normotensive girls between 8 and 13 years, and no association was observed for growth-velocity. In conclusion, rapid linear growth between 8 and 13 years predicts elevated adult blood pressure in boys. This association is likely to reflect relatively early onset of puberty among hypertensive males. |
| | |
Authors:
|
Thorhallur Ingi Halldorsson; Ingibjorg Gunnarsdottir; Bryndis Eva Birgisdottir; Vilmundur Gudnason; Thor Aspelund; Inga Thorsdottir |
Related Documents
:
|
22229134 - A comparison between two different alveolar recruitment maneuvers in patients with acut... 22266494 - Elevated intracranial pressure management. 21724004 - Effects of prophylactic continuous infusion of phenylephrine on reducing the mass of lo... 21881404 - A case-based approach to noninvasive positive pressure ventilation. 11385824 - Effects of time pressure on mechanisms of speech production and self-monitoring. 7065484 - Effect of flunarizine on canine cerebral cortical blood flow and vascular resistance po... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-5-16 |
Journal Detail:
|
Title: Hypertension Volume: - ISSN: 1524-4563 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
|
Created Date: 2011-5-17 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7906255 Medline TA: Hypertension Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Unit for Nutrition Research, University of Iceland and Landspitali University Hospital, Reykjavik, Iceland; Faculties of Food Science and Nutrition and Medicine, School of Health Sciences, and Faculty of Medicine, Center of Public Health Sciences, University of Iceland, Reykjavik, Iceland; Icelandic Heart Association, Kopavogur, Iceland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Hospital mortality, length of stay, and preventable complications among critically ill patients befo...
Next Document: Angiotensin II type 1 receptor antibodies and increased angiotensin II sensitivity in pregnant rats.