| The Childhood Cancer Survivor Study: a National Cancer Institute-supported resource for outcome and intervention research. | |
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MedLine Citation:
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PMID: 19364948 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Survival for childhood cancer has increased dramatically over the last 40 years with 5-year survival rates now approaching 80%. For many diagnostic groups, rapid increases in survival began in the 1970s with the broader introduction of multimodality approaches, often including combination chemotherapy with or without radiation therapy. With this increase in rates of survivorship has come the recognition that survivors are at risk for adverse health and quality-of-life outcomes, with risk being influenced by host-, disease-, and treatment-related factors. In 1994, the US National Cancer Institute funded the Childhood Cancer Survivor Study, a multi-institutional research initiative designed to establish a large and extensively characterized cohort of more than 14,000 5-year survivors of childhood and adolescent cancer diagnosed between 1970 and 1986. This ongoing study, which reflects the single most comprehensive body of information ever assembled on childhood and adolescent cancer survivors, provides a dynamic framework and resource to investigate current and future questions about childhood cancer survivors. |
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Authors:
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Leslie L Robison; Gregory T Armstrong; John D Boice; Eric J Chow; Stella M Davies; Sarah S Donaldson; Daniel M Green; Sue Hammond; Anna T Meadows; Ann C Mertens; John J Mulvihill; Paul C Nathan; Joseph P Neglia; Roger J Packer; Preetha Rajaraman; Charles A Sklar; Marilyn Stovall; Louise C Strong; Yutaka Yasui; Lonnie K Zeltzer |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review Date: 2009-04-13 |
Journal Detail:
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Title: Journal of clinical oncology : official journal of the American Society of Clinical Oncology Volume: 27 ISSN: 1527-7755 ISO Abbreviation: J. Clin. Oncol. Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-05-08 Completed Date: 2009-05-15 Revised Date: 2010-09-24 |
Medline Journal Info:
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Nlm Unique ID: 8309333 Medline TA: J Clin Oncol Country: United States |
Other Details:
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Languages: eng Pagination: 2308-18 Citation Subset: IM |
Affiliation:
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Department of Epidemiology and Cancer Control, St Jude Children's Research Hospital, Memphis, TN 38105-2794, USA. les.robison@stjude.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Age Factors Child Cohort Studies Demography Female Follow-Up Studies Forecasting Health Services Accessibility Humans Male Multicenter Studies as Topic National Cancer Institute (U.S.) / economics Neoplasms / mortality*, therapy* Population Surveillance Quality of Life* Research Design Resource Allocation / statistics & numerical data, trends Survival Rate Survivors / statistics & numerical data* Tissue Banks Treatment Outcome United States / epidemiology |
| Grant Support | |
ID/Acronym/Agency:
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U24 CA 55727/CA/NCI NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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