Document Detail

Chikungunya fever. Rheumatic manifestations of an emerging disease in Europe.
MedLine Citation:
PMID:  25192946     Owner:  NLM     Status:  Publisher    
Chikungunya fever is a viral disease caused by an alphavirus belonging to the Togaviridae family, transmitted by several species of Aedes mosquitoes: Aedes aegypti and Aedes albopictus (A. albopictus). It is endemic in Africa and Asia with recurrent outbreaks. It is an emerging disease and cases in Europe transmitted by A. albopictus have been established in Mediterranean areas. The first autochthonous cases detected on the Caribbean islands suppose a serious threat of spreading disease to America, which so far has been disease free. Clinical symptoms begin abruptly with fever, skin rash and polyarthritis. Although mortality is low, a high percentage of patients develop a chronic phase defined by persistent arthritis for months or even years. A severe immune response is responsible for joint inflammation. The absence of specific treatment and lack of vaccine requires detailed studies about its immunopathogenesis in order to determine the most appropriate target.
M Loreto Horcada; Carlos Díaz-Calderón; Laura Garrido
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-9-2
Journal Detail:
Title:  Reumatologia clinica     Volume:  -     ISSN:  1885-1398     ISO Abbreviation:  Reumatol Clin     Publication Date:  2014 Sep 
Date Detail:
Created Date:  2014-9-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101293923     Medline TA:  Reumatol Clin     Country:  -    
Other Details:
Languages:  ENG; SPA     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier España, S.L.U. All rights reserved.
Vernacular Title:
Fiebre chikungunya. Manifestaciones reumáticas de una infección emergente en Europa.
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