Document Detail

Chicken extract affects colostrum protein compositions in lactating women.
MedLine Citation:
PMID:  14711459     Owner:  NLM     Status:  MEDLINE    
This study investigated the effect of supplementation with chicken extract on plasma and colostrum protein compositions in lactating women. Thirty healthy pregnant women were evenly divided into the control (n = 15) or chicken extract (CE) group (n = 15). The CE group was given one bottle (70 mL/bottle) of chicken extract three times a day to provide 18 g protein from the 37th week pregnancy to 3 days postpartum. All women in the CE group consumed chicken extract at least for 2 weeks (18 +/- 5 days). High protein supplement was restricted in the control group. Blood samples were collected during the 37th week pregnancy and 3-day postpartum, and milk was collected during 3-day postpartum. The results showed that plasma total protein was significantly lower by 14% in the CE group compared with that in the control group during 3-day postpartum. Plasma epidermal growth factor (EGF) significantly elevated by 236% during 3-day postpartum compared with those during the 37th week pregnancy in the CE group. The levels of lactoferrin, EGF, and transforming growth factor-beta2 (TGF-beta2) in colostrum significantly increased by 34%, 62%, and 196%, respectively, in the CE group compared with those in the control group. However, the levels of total protein, casein, lactalbumin, and secretory immunoglobulin A in colostrum did not significantly differ between two groups. Therefore, supplementation with chicken extract increased colostrum levels of lactoferrin, EGF, and TGF-beta2, which are important for the growth and immune functions of the infants, in lactating women.
Jane C-J Chao; Hsu-Ping Tseng; Ching Wen Chang; Yi-Yi Chien; Heng Kien Au; Jiun-Rong Chen; Chin-Fa Chen
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  The Journal of nutritional biochemistry     Volume:  15     ISSN:  0955-2863     ISO Abbreviation:  J. Nutr. Biochem.     Publication Date:  2004 Jan 
Date Detail:
Created Date:  2004-01-08     Completed Date:  2004-08-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9010081     Medline TA:  J Nutr Biochem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  37-44     Citation Subset:  IM    
Graduate Institute of Nutrition and Health Sciences, Taipei Medical University, Taipei, Taiwan 110.
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MeSH Terms
Blood Proteins / drug effects,  metabolism*
Body Constitution
Epidermal Growth Factor / blood
Gestational Age
Infant, Newborn
Lactation / drug effects,  physiology*
Milk Proteins / drug effects,  metabolism*
Tissue Extracts / pharmacology*
Reg. No./Substance:
0/Blood Proteins; 0/Milk Proteins; 0/Tissue Extracts; 62229-50-9/Epidermal Growth Factor

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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