Document Detail


Chiasma syndrome in acromegalic patients--correlation of neuroradiologic and neuroophthalmologic findings.
MedLine Citation:
PMID:  12528288     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The study evaluated neuroophthalmologic and computerized tomography (CT) findings in 100 patients with somatotrophic adenoma and clinical picture of acromegaly, who underwent transsphenoidal adenomectomy. Prior to the surgery, visual field was normal in 77 patients. The diameter of adenoma in these patients ranged from 8 to 30 mm on CT, and the average value was 13.5 mm. Various kinds of visual field disturbances were present in 23 patients. The diameter of their adenomas ranged between 18 to 35 mm, with the average of 24.7 mm. Compared to visual field defects, CT findings of suprasellar adenoma extension were better correlated with chiasma syndrome (p < 0.001). All patients with suprasellar mass greater than 10 mm had chiasma syndrome. Degenerative adenoma changes (hemorrhagic necrosis), which precipitate abrupt increase in size of the tumor, were more frequently seen in patients with chiasma syndrome. The incidence of chiasma syndrome directly correlates with the degree of suprasellar extension of the tumor.
Authors:
Z Gnjidić; R Iveković; Z Rumboldt; M Malenica; B Vizner; M Berković
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Collegium antropologicum     Volume:  26     ISSN:  0350-6134     ISO Abbreviation:  Coll Antropol     Publication Date:  2002 Dec 
Date Detail:
Created Date:  2003-01-16     Completed Date:  2003-02-13     Revised Date:  2009-02-04    
Medline Journal Info:
Nlm Unique ID:  8003354     Medline TA:  Coll Antropol     Country:  Croatia    
Other Details:
Languages:  eng     Pagination:  601-8     Citation Subset:  IM    
Affiliation:
Department of Neurosurgery, University Hospital Sestre Milosrdnice, Zagreb, Croatia.
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MeSH Terms
Descriptor/Qualifier:
Acromegaly / etiology*
Adenoma / complications,  diagnosis*,  surgery
Adult
Female
Humans
Male
Pituitary Neoplasms / complications,  diagnosis*,  surgery
Tomography, X-Ray Computed
Visual Fields*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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