Document Detail

Chiari 1 malformation with syringomyelia: correlation of phase-contrast cine MR imaging and outcome.
MedLine Citation:
PMID:  17939105     Owner:  NLM     Status:  MEDLINE    
AIM: This study was designed to determine the hemodynamics of cerebrospinal fluid flow in syringomyelia patients associated with Chiari I malformation using phase-contrast velocity-encoded-cine MRI and also to find out whether treatment outcomes may be predicted by these flow measurements. MATERIAL AND METHODS: Eighteen consecutive symptomatic patients with syringomyelia associated with Chiari 1 malformation were included. The PC VEC MRI was performed at the level of foramen magnum and syrinx cavity both preoperatively and 6 months postoperatively. Following surgery, the modified Asgari score was calculated, and the association between CSF flow pattern and clinical outcome was assessed. RESULTS: Evaluation of clinical symptoms at postoperative 6th month revealed improvement in 11 (61%) patients and stabilization in 5 (28%) patients whereas results were poor in 2 (11%) patients. Preoperative cine MRI flow studies showed a heterogeneous pattern at the foramen magnum level in all of the patients. Postoperative cine MR flow studies demonstrated the change from heterogeneous pattern to sinusoidal pattern in 11 patients and a decrease in heterogeneity in 7 patients. CONCLUSION: Our results indicate that CSF flow measurements using PC VEC MRI can give important information regarding the prognosis and follow-up of the patients with Chiari I malformation.
Kenan Koç; Yonca Anik; Ihsan Anik; Burak Cabuk; Savaş Ceylan
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Turkish neurosurgery     Volume:  17     ISSN:  1019-5149     ISO Abbreviation:  Turk Neurosurg     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-10-16     Completed Date:  2008-04-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9423821     Medline TA:  Turk Neurosurg     Country:  Turkey    
Other Details:
Languages:  eng     Pagination:  183-92     Citation Subset:  IM    
Kocaeli University School of Medicine, Neurosurgery, Kocaeli, Turkey.
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MeSH Terms
Arnold-Chiari Malformation / pathology*,  physiopathology,  surgery*
Cerebrospinal Fluid / physiology
Follow-Up Studies
Foramen Magnum
Magnetic Resonance Imaging / methods*
Middle Aged
Syringomyelia / pathology*,  physiopathology,  surgery*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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