| Chest wall rigidity in two infants after low-dose fentanyl administration. | |
| | |
MedLine Citation:
|
PMID: 22561320 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
ABSTRACT: Since its introduction into clinical practice, it has been known that fentanyl and other synthetic opioids may cause skeletal muscle rigidity. Involvement of the respiratory musculature, laryngeal structures, or the chest wall may impair ventilation, resulting in hypercarbia and hypoxemia. Although most common with the rapid administration of large doses, this rare adverse effect may occur with small doses especially in neonates and infants. We present 2 infants who developed chest wall rigidity, requiring the administration of neuromuscular blocking agents and controlled ventilation after analgesic doses of fentanyl. Previous reports regarding chest wall rigidity after the administration of low-dose fentanyl in infants and children are reviewed, the pathogenesis of the disorder is discussed, and treatment options offered. |
| | |
Authors:
|
Elisabeth Dewhirst; Aymen Naguib; Joseph D Tobias |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Pediatric emergency care Volume: 28 ISSN: 1535-1815 ISO Abbreviation: Pediatr Emerg Care Publication Date: 2012 May |
Date Detail:
|
Created Date: 2012-05-07 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8507560 Medline TA: Pediatr Emerg Care Country: United States |
Other Details:
|
Languages: eng Pagination: 465-8 Citation Subset: IM |
Affiliation:
|
From the Departments of *Anesthesiology and †Pediatrics, Nationwide Children's Hospital and the Ohio State University, Columbus, OH. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Transdermal fentanyl in deliberate overdose in pediatrics.
Next Document: Life-Threatening Rhabdomyolysis Induced by Streptococcus bovis Sepsis in a 6-Year-Old Girl Presented...