| Chest compressions versus ventilation plus chest compressions in a pediatric asphyxial cardiac arrest animal model. | |
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MedLine Citation:
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PMID: 20148320 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To compare the ventilation achieved with chest compressions (CC) or ventilation plus compressions (VC) in a pediatric animal model of cardiac arrest. DESIGN: Randomized experimental study. SETTING: Experimental department of a University Hospital. METHODS: Twelve infant pigs with asphyxial cardiac arrest. Sequential 3-min periods of VC and CC were performed for a total duration of 9 min. Tidal volume (TV), end-tidal CO(2) (EtCO(2)), mean arterial pressure (MAP), central venous pressure (CVP), mean pulmonary arterial pressure (mPAP), and peripheral, cerebral, and renal saturations were recorded and arterial and venous blood gases were analyzed. RESULTS: VC achieved a TV similar to the preset parameters on the ventilator, whilst the TV in CC was very low (P < 0.001). EtCO(2) with VC was significantly higher than with CC (14.0 vs. 3.9 mmHg, P < 0.05). Arterial pH was higher with VC than with CC (6.99 vs. 6.90 mmHg, P < 0.05). Arterial PCO(2) was lower with VC than with CC (62.1 vs. 97.0 mmHg, P < 0.05). There were no significant differences in the MAP; CVP; mPAP; peripheral, renal, and cerebral saturations; or lactate concentrations between the two techniques. CONCLUSIONS: VC achieves better ventilation than CC during cardiopulmonary resuscitation and has no negative effect on the hemodynamic situation. |
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Authors:
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Jose Mar?a Iglesias; Jes?s L?pez-Herce; Javier Urbano; Maria Jos? Solana; Santiago Menc?a; Jimena Del Castillo |
Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't Date: 2010-02-11 |
Journal Detail:
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Title: Intensive care medicine Volume: 36 ISSN: 1432-1238 ISO Abbreviation: Intensive Care Med Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-03-12 Completed Date: 2010-06-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7704851 Medline TA: Intensive Care Med Country: United States |
Other Details:
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Languages: eng Pagination: 712-6 Citation Subset: IM |
Affiliation:
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Pediatric Intensive Care Service, Hospital General Universitario Gregorio Mara??n, Dr Castelo 47, 28009, Madrid, Spain. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Animals, Newborn Asphyxia / physiopathology, therapy* Blood Gas Analysis Cardiopulmonary Resuscitation / methods* Disease Models, Animal Heart Arrest / physiopathology, therapy* Heart Massage / methods* Respiration, Artificial / methods* Statistics, Nonparametric Swine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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