Document Detail

Chest compressions versus ventilation plus chest compressions in a pediatric asphyxial cardiac arrest animal model.
MedLine Citation:
PMID:  20148320     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To compare the ventilation achieved with chest compressions (CC) or ventilation plus compressions (VC) in a pediatric animal model of cardiac arrest. DESIGN: Randomized experimental study. SETTING: Experimental department of a University Hospital. METHODS: Twelve infant pigs with asphyxial cardiac arrest. Sequential 3-min periods of VC and CC were performed for a total duration of 9 min. Tidal volume (TV), end-tidal CO(2) (EtCO(2)), mean arterial pressure (MAP), central venous pressure (CVP), mean pulmonary arterial pressure (mPAP), and peripheral, cerebral, and renal saturations were recorded and arterial and venous blood gases were analyzed. RESULTS: VC achieved a TV similar to the preset parameters on the ventilator, whilst the TV in CC was very low (P < 0.001). EtCO(2) with VC was significantly higher than with CC (14.0 vs. 3.9 mmHg, P < 0.05). Arterial pH was higher with VC than with CC (6.99 vs. 6.90 mmHg, P < 0.05). Arterial PCO(2) was lower with VC than with CC (62.1 vs. 97.0 mmHg, P < 0.05). There were no significant differences in the MAP; CVP; mPAP; peripheral, renal, and cerebral saturations; or lactate concentrations between the two techniques. CONCLUSIONS: VC achieves better ventilation than CC during cardiopulmonary resuscitation and has no negative effect on the hemodynamic situation.
Jose Mar?a Iglesias; Jes?s L?pez-Herce; Javier Urbano; Maria Jos? Solana; Santiago Menc?a; Jimena Del Castillo
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-02-11
Journal Detail:
Title:  Intensive care medicine     Volume:  36     ISSN:  1432-1238     ISO Abbreviation:  Intensive Care Med     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-12     Completed Date:  2010-06-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7704851     Medline TA:  Intensive Care Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  712-6     Citation Subset:  IM    
Pediatric Intensive Care Service, Hospital General Universitario Gregorio Mara??n, Dr Castelo 47, 28009, Madrid, Spain.
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MeSH Terms
Animals, Newborn
Asphyxia / physiopathology,  therapy*
Blood Gas Analysis
Cardiopulmonary Resuscitation / methods*
Disease Models, Animal
Heart Arrest / physiopathology,  therapy*
Heart Massage / methods*
Respiration, Artificial / methods*
Statistics, Nonparametric

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