| Chest pain in the emergency room: a multicenter validation of the HEART Score. | |
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MedLine Citation:
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PMID: 20802272 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Decision-making in chest pain patients is hampered by poor diagnostic power of patient's history, electrocardiogram, age, risk factors, and troponin. Each of these findings may be qualified with 0, 1, or 2 points. Together they compose the HEART score. We tested the hypothesis that the HEART score predicts major adverse cardiac events. DESIGN: Retrospective multicenter analysis in patients presenting at the cardiology emergency room. SETTING: Patient inclusion between January 1 and March 31, 2006. PATIENTS: A total of 2161 patients were admitted, of which 910 patients (42%) presented with chest pain. Analysis was performed in 880 cases (96.7%). MAIN OUTCOME MEASURES: The primary endpoint was a composite of acute myocardial infarction, percutaneous coronary intervention, coronary artery bypass graft surgery and death, within 6 weeks after presentation, together called major adverse cardiac events. RESULTS: A total of 158 patients (17.95%) reached the primary endpoint. Ninety-two patients had an acute myocardial infarction (10.45%), 82 a percutaneous coronary intervention (9.32%), 36 a coronary artery bypass graft (4.09%), and 13 died (1.48%). Of 303 patients with HEART score 0 to 3, three (0.99%) had an endpoint. In 413 patients with HEART score 4 to 6, 48 cases (11.6%) reached an endpoint. In case of a HEART score of 7 to 10, an endpoint was reached in 107/164 cases (65.2%). CONCLUSIONS: The HEART score helps in making accurate diagnostic and therapeutic decisions without the use of radiation or invasive procedures. The HEART score is an easy, quick, and reliable predictor of outcome in chest pain patients and can be used for triage. |
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Authors:
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Barbra E Backus; A Jacob Six; Johannes C Kelder; Thomas P Mast; Frederieke van den Akker; E Gijis Mast; Stefan H J Monnink; Rob M van Tooren; Pieter A F M Doevendans |
Publication Detail:
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Type: Journal Article; Multicenter Study; Validation Studies |
Journal Detail:
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Title: Critical pathways in cardiology Volume: 9 ISSN: 1535-2811 ISO Abbreviation: Crit Pathw Cardiol Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-30 Completed Date: 2010-12-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101165286 Medline TA: Crit Pathw Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 164-9 Citation Subset: IM |
Affiliation:
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Department of Cardiology, Universitair Medisch Centrum, Utrecht, Nieuwegein, The Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angioplasty, Balloon, Coronary
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methods Biological Markers / blood Chest Pain / diagnosis*, mortality, therapy Cohort Studies Coronary Angiography / methods Coronary Artery Bypass / methods Diagnostic Techniques, Cardiovascular / standards* Early Diagnosis Electrocardiography Emergency Service, Hospital / utilization* Female Humans Kaplan-Meier Estimate Male Myocardial Infarction / diagnosis*, mortality, therapy Prognosis Retrospective Studies Risk Assessment Severity of Illness Index Survival Analysis Troponin T / blood* |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Troponin T |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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