Document Detail


Chemotherapy and multimodality treatment in thyroid carcinoma.
MedLine Citation:
PMID:  1694985     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
With the combination of pre- and postoperative chemotherapy and radiotherapy, the majority of patients with anaplastic giant cell thyroid carcinoma will achieve local tumor control. A few patients may even be cured by this treatment. Only few patients with differentiated thyroid carcinoma respond to chemotherapy treatment. However, at present it is not possible to discern these few. Chemotherapy for advanced thyroid carcinoma cannot as yet be routinely recommended. Doxorubicin, cisplatin, and VP16 are the drugs currently considered most effective. Side effects may be severe. Multimodality treatment may be an alternative.
Authors:
E T Ekman; G Lundell; J Tennvall; G Wallin
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Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  Otolaryngologic clinics of North America     Volume:  23     ISSN:  0030-6665     ISO Abbreviation:  Otolaryngol. Clin. North Am.     Publication Date:  1990 Jun 
Date Detail:
Created Date:  1990-08-13     Completed Date:  1990-08-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0144042     Medline TA:  Otolaryngol Clin North Am     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  523-7     Citation Subset:  IM    
Affiliation:
Department of General Oncology, Radiumhemmet, Karolinska Hospital, Stockholm, Sweden.
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MeSH Terms
Descriptor/Qualifier:
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Bleomycin / administration & dosage*
Carcinoma / drug therapy*,  radiotherapy,  surgery
Doxorubicin / administration & dosage*
Humans
Methotrexate / administration & dosage*
Postoperative Care
Preoperative Care
Radiotherapy Dosage
Remission Induction
Thyroid Neoplasms / drug therapy*,  radiotherapy,  surgery
Thyroidectomy
Chemical
Reg. No./Substance:
11056-06-7/Bleomycin; 23214-92-8/Doxorubicin; 59-05-2/Methotrexate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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