| Chemotherapy-induced reversible posterior leucoencephalopathy syndrome. | |
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MedLine Citation:
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PMID: 20446957 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Reversible posterior leucoencephalopathy syndrome is a neurological condition seen in various areas of acute medicine, including the administration of antineoplastic therapies used in haemato-oncology patients. It is a rare complication that has been increasingly recognized. It is characterized by altered mental status, visual disturbance, headache and seizures. Magnetic resonance imaging typically shows vasogenic oedema in the posterior regions of the brain. Although its name suggests reversibility, it may result in an irreversible brain injury without prompt treatment. Therefore, it is vital for treating clinicians to recognize this syndrome. We describe the case of a 55-year-old woman with advanced pancreatic adenocarcinoma, who developed clinical and radiological manifestations consistent with this syndrome as a complication of gemcitabine monotherapy. |
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Authors:
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C H Han; M P Findlay |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Internal medicine journal Volume: 40 ISSN: 1445-5994 ISO Abbreviation: Intern Med J Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-05-07 Completed Date: 2011-01-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101092952 Medline TA: Intern Med J Country: Australia |
Other Details:
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Languages: eng Pagination: 153-9 Citation Subset: IM |
Affiliation:
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Department of Medical Oncology, Auckland City Hospital, Auckland, New Zealand. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antineoplastic Agents
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adverse effects* Deoxycytidine / adverse effects, analogs & derivatives* Female Humans Middle Aged Posterior Leukoencephalopathy Syndrome / chemically induced*, diagnosis* |
| Chemical | |
Reg. No./Substance:
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0/Antineoplastic Agents; 103882-84-4/gemcitabine; 951-77-9/Deoxycytidine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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